João Carlos Serafim Varela
Professor auxiliar
Faculdade de Ciências e Tecnologia
Centro de Ciências do Mar
Subsistema
Docentes Universitário
Unidade ID
Centro de Ciências do Mar
Regime
Exclusividade
Vínculo
CT em Funções Públicas por tempo indeterminado
Atividades
Atividades
2021/01/01 - 2024/12/31. Orientação. Inês Maia - Bioremediation of hydroponic production drain water using a microalgae-based circular economy approach for sustainable aquaculture and agriculture products. PhD project..Programa Doutoral em Ciências do Mar, da Terra e do Ambiente (Doutoramento). Orientador.
2020/09/01 - 2024/08/31. Orientação. Nádia Correia - Industrial cultivation of microalgae as a sustainable alternative for brewery wastewater treatment for feed and biostimulant applications. PhD Project..Programa Doutoral em Ciências do Mar, Terra e Ambiente (Doutoramento). Orientador.
2023 - Presente. Orientação. Development of a sustainable multiproduct biorefinery for brown algae biomass..Marine Biotechnology (Doutoramento). Orientador.
2023 - Presente. Orientação. Strain improvement of the industrial marine microalga Nannochloropsis sp. for the production of omega-3 fatty acids from sunlight..Marine Biotechnology (Doutoramento). Orientador.
2023 - Presente. Orientação. Development of an online LCA monitoring tool for improved sustainability of microalgae production in hydroponic drain water. .Marine Biotechnology. Coorientador.
2023 - Presente. Orientação. Tailoring microalgae for a sustainable bioprocess in aquafeed applications..Marine Biotechnology (Doutoramento). Coorientador.
2023 - Presente. Orientação. Development of innovative diets with industrially-produced microalgae to optimize nutrition and biological performance in bivalves. .Marine Biotechnology (Doutoramento). Coorientador.
2023 - Presente. Orientação. A pathway towards better health: fighting inflammation with novel microalgae-based natural compounds. .Biotecnologia Marinha (Doutoramento). Coorientador.
2017 - 2022. Orientação. Biomass value upgrade of a stress-resistant, lipid-rich marine microalga (Tetraselmis sp. CTP4) - SFRH/BD/115325/2016.Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2021/09/01 - 2022. Orientação. Contaminant detection in industrial microalgal cultures.Mestrado em Biologia Molecular e Microbiana (Mestrado). Orientador.
2020/09/01 - 2022. Orientação. Nutritional effects of microalgae-fed rotifer blends on the growth and development of zebrafish.Mestrado em Aquacultura e Pescas (Mestrado). Orientador.
2020/09/01 - 2022. Orientação. The development of a marketing plan for the commercialization of a new supplement in the Portuguese market.Mestrado em Gestão (Mestrado). Coorientador.
2020/09/01 - 2022. Orientação. Isolation of two novel Chlorella vulgaris and Tetraselmis chui mutants with improved protein contents and pigments for food applications.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2021/12/01 - 2022. Orientação. Development of a novel microalgae-based eicosapentaenoic acid (EPA) supplement for the nutraceuticals market.Programa Doutoral de Ciências da Terra do Mar e do Ambiente (Doutoramento). Orientador.
2022 - Presente. Orientação. The impact of high temperature and CO2 levels on microalgae growth, transcriptome and metabolome. .Marine Biotechnology (Doutoramento). Coorientador.
2020/09/01 - 2022/11. Orientação. Industrial production of diatoms Skeletonema costatum and Chaetoceros calcitrans.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2020/09/01 - 2021. Orientação. 3D printed glúten-free cereal snack with incorporation of Spirulina (Arthrospira platensis) and/or Chlorella vulgaris.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2020/09/01 - 2021. Orientação. Assessment of microalgal biomass as potential feedstock for sustainable, eco-friendly biostimulants and biopesticides in plant production.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2020/09/01 - 2021/09. Orientação. Effect of microalgal biomass on the strawberry (Fragaria x ananassa) yield and quality.Mestrado em Biologia Marinha. Coorientador.
2021/09/01 - Presente. Orientação. Production and formulation of an Arthrospira platensis protein-based meat analogue.Programa Doutoral em Ciências do Mar, Terra e do Ambiente (Doutoramento). Orientador.
2020/12/03. Apresentação oral de trabalho. Santos, T., Pereira, H., Navalho, J., Engelen, A., Silva, J., Varela, J. (2020) Bacterial community associated with the industrial production of Tisochrysis lutea. ALGAEUROPE 2020, 1-4 December. Virtual meeting. Oral presentation.. ALGAEUROPE 2020, 1-4 December.. Virtual.
2020/12/03. Apresentação oral de trabalho. Barreira, L., Morais, E.G., Cerqueira, P.R., Pena. A., Marques, J., Dimas, C., Teixeira, M., Varela, J. (2020) Urban wastewater treatment with microalgae in a pilot-scale plant: nutrients recovery and pharmaceuticals removal.. ALGAEUROPE 2020, 1-4 December. Virtual meeting. Oral presentation..
2020/10/26. Apresentação oral de trabalho. Carletti, A., Santos, T., Katkam, G.N., Cristofoli, N., Barreira, L., Pereira, H., Varela, J., Laizé, V., Cancela, M.L., Gavaia, P.J. (2020) Bioprospection using zebrafish: the potential of Tetraselmis sp. CTP4 as a source for bone anabolic compounds.. 11th European Zebrafish Meeting. October 26-27, 2020..
2020/10/26. Apresentação oral de trabalho. Diogo, P., Martins, G., Santos, T., Cabrita, E., del Pino, V., Navalho, J., Varela, J., Gavaia, P. (2020). Sustainable microalgae products to improve zebrafish reproduction and larvae development.11th Zebrafish Meeting. October 26-27. 11th Zebrafish Meeting. October 26-27.
2019/09/01 - 2020/09/30. Orientação. Farmacogenómica aplicada ao tratamento antirretroviral em Portugal,.Mestrado em Ciências Farmacêuticas (Mestrado). Orientador.
2015 - 2019. Orientação. Biotechnological applications of a promising marine chlorophyte (Tetraselmis sp. CTP4): biomass upgrading considering a biorefinery approach. SFRH/BD/105541/2014..Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2018 - 2019. Orientação. Development of a commercial microalgae enrichment of live feed for zebrafish.Mestrado em Aquacultura e Pescas (Mestrado). Coorientador.
2019 - 2019. Orientação. Phycobiliproteins accumulation in a cyanobacterium isolated from an extreme environment.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2019 - 2019. Orientação. Improvement of Gracilaria gracilis efficiency as ingredient in European seabass diets.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2019 - 2019. Orientação. The effect of nutrient concentration and production system on bioactive compounds of Ulva spp. cultivated in different integrated systems.Mestrado em Aquacultura e Pescas (Mestrado). Coorientador.
2019/12/04 - 2019/12/06. Participação em evento. Schüler, L.M., Duarte, p., Barreira, L., Varela, J. (2019). Isolation of carotenoid-hyperproducing mutants of Tetraselmis sp. CTP4 by fluorescence-activated cell sorting. Congresso. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/04 - 2019/12/06. Participação em evento. Santos, T., Pereira, H., Cristofoli, N., Barbosa, J., Maia, I., Barreira, L., Varela, J. (2019). Isolation and characterization of new microalgae strains from the southern Portuguese coast: focus on nutritional and bioactive properties with nutraceutical applications. Congresso. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/04 - 2019/12/06. Participação em evento. Santos, T., Pereira, H., Navalho, J., Engelen, A., Silva, J., Varela, J. (2019). Microbiome-mediated improvement of industrial produced microalgae. . Congresso. ALGAEUROPE, Paris, France, 4-6 December.
2019/12/04 - 2019/12/06. Participação em evento. Maia, I., Carneiro, M., Navalho, J., Pereira, H., Varela, J. (2019). Let there be light: fluorescence response of three diatoms grown in pilot-scale flat panels. . Congresso. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/04 - 2019/12/06. Participação em evento. Pereira, H., Sá, M., Teles, I., Varela, J., Wijffels, R., Barbosa, M., Navalho, J. (2019). Biomass and target metabolites productivities of Tisochrysis lutea produced in industrial photobioreactors. Congresso. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/06. Apresentação oral de trabalho. Katkam, G.N., Gaspar, H., Pereira, H., Malcata, F.X., Varela, J., Barreira, L. (2019). Cytotoxicity and toxicity of loliolides, monoterpene lactones isolated from the marine microalga, Tisochrysis lutea.. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/04 - 2019/12/06. Participação em evento. Monteiro, I., Cardoso, C., Castanho, S., Gomes, A., Afonso, C., Santos, T., Cristofoli, N., Soares, F., Varela, J., Bandarra, N., Pousão-Ferreira, P. (2019). Enrichment of Brachionus spp. and Artemia sp. with new microalgae strains. . Congresso. ALGAEUROPE, Paris, France, 4-6 December..
2019/12/04 - 2019/12/06. Participação em evento. Morais, E., Cerqueira, R., Teixeira, M.M., Varela, J., Barreira, L. (2019). Wastewater treatment by microalgae isolated from an urban effluent. . Congresso. ALGAEUROPE, Paris, France, 4-6 December.
2019/12/05. Apresentação oral de trabalho. Varela, J., Santos, T., Barreira, L., Schüler, L, Katkam, G., Cristofoli, N., Barbosa, J.P., Bombo, G., Ismael, K., Pereira, H., Navalho, J., Marreiros, C., Viegas, C., Simes, D., Ferreira, B.I., Silva, A., Link, W., Carletti, A., Varela, T., Gavaia, P., Laizé, V., Cancela, M.L. (2019). ALGARED+: Old and new microalgae for novel bioactivities. ALGAEUROPE, Paris, France, 4-6 December.. ALGAEUROPE (Paris, França).
2019/09/01. Apresentação oral de trabalho. Marreiros, C., Ismael, K., Viegas, C., Araújo, N., Andrade, M., Rosa, B., Lima, R., Santos-Fernandes, V., Barreira, L., Varela, J., Simes, D. Anti-Inflammatory Activity of Microalgae-Derived Bioactives with Potential Dermoprotective Application Chronic Inflammation in Skin Isolation of Microalgae Extracts From Four Selected Algae Species: Experimental Design and Methods. . XVI MaNaPro & XI ECMNP, 2019, 1-5 September, Peniche, Portugal..
2018 - Presente. Orientação. BIOALGAE. Development of cosmeceutical ingredients, PUFA-rich dietary supplements, microalgae-based lecithin as food emulsifier, lipoamino-conjugate derivatives for pharmaceutical applications, and bioactive compounds from microalgal biomass using a Biorefinery approach..FCT Researcher (Outra). Orientador.
2018 - Presente. Orientação. Microbiome-mediated improvement of industrial Chlorella biomass production - SFRH/BD/140143/2018.Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2018 - 2018. Orientação. Prospection, of bioactivities, bioaccessibility, and biochemical characterization of green seaweeds grown in integrated multi-trophic aquaculture environments.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2018 - 2018. Orientação. Farmacogenómica da depressão..Mestrado em Ciências Farmacêuticas (Mestrado). Orientador.
2018/12/04 - 2018/12/06. Participação em evento. Schüler, L., Placines, C., Katkam, G., Barreira, L., Varela, J. (2018) Carotenoid extraction of a stress resistant, lipid-rich microalga Tetraselmis sp. CTP4. . Congresso. ALGAEUROPE, Amsterdam, The Netherlands, 3-5 December..
2018/12/04 - 2018/12/06. Participação em evento. Santos, T., Pereira, H., Barbosa, J., Barreira, L., Varela, J. (2018). Isolation of microalgae from Algarve coastal waters for bioactivity discovery within the ALGARED+ network. . ALGAEUROPE, Amsterdam, The Netherlands, 4-6 December..
2018/12/04 - 2018/12/06. Participação em evento. Salazar, J., Barreira, L., Varela, J., Pereira, H., Katkam, G. (2018) Lab-Scale Improvement of Growth Productivity and Fucoxanthin Extraction of Isochrysis galbana. . Congresso. ALGAEUROPE, Amsterdam, The Netherlands, 4-6 December.
2018/12/04 - 2018/12/06. Participação em evento. Maia, I, Pereira, H, Santos, T., Tarasco, M., Laizé, V., Gavaia, P., Cancela, L., Navalho, J., Barreira, L., Varela, J. (2018). Lab-scale optimization of abiotic growth parameters and in vivo osteogenic activity of Emiliania huxleyi. . Congresso. ALGAEUROPE, Amsterdam, The Netherlands, 4-6 December.
2018/12/05. Apresentação oral de trabalho. Pereira, H., Katkam, G., Silva, J., Sarinha, M., Santos, T., Navalho, J., Gouveia, L., Barreira, L., Dias, J., Varela, J. (2018) Industrial production of Tetraselmis sp. CTP4 for different biorefinery-based biotechnological applications. ALGAEUROPE, Amsterdam, The Netherlands, 4-6 December..
2018/12/05. Apresentação oral de trabalho. Navalho, J., del Pino, V., Póvoa, I., Compadre, A., Santos, T., Franco, J., Matos, J., Cardoso, C., Afonso, C., Bandarra, N., Varela, J., Pereira, H. (2018) High density production of the diatom, Skeletonema sp. in industrial closed tubular photobioreactors: biochemical profiling of biomass for feed applications. . ALGAEUROPE, Amsterdam, The Netherlands, 4-6 December..
2012 - 2017. Orientação. Synthesis of novel lipid derivatives from vegetable oils and their processing by-products for nutraceutical and industrial applications..Post-doc - SFRH/BPD/81882/2011 (Outra). Coorientador.
2017 - Presente. Orientação. Improvement of lipid production processes by microalgae in a novel photobioreactor.Programa Doutoral - LEPABE (Doutoramento). Coorientador.
2012 - 2017. Orientação. Marine Algae Extracts As A Source Of Natural Antileishmanial Compounds - SFRH/BD/78062/2011.Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2017 - 2017. Orientação. Searching for biocompounds in algae and seagrasses with potential use in the treatment of Alzheimer’s disease.Mestrado Integrado em Engenharia Biológica (Mestrado). Coorientador.
2017 - 2017. Orientação. Farmacogenómica do cancro colorretal.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2017 - 2017. Orientação. Diabetes Mellitus 2 como doença inflamatória: anatomia, fisiopatologia e terapêutica.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2017 - 2017. Orientação. Aplicação de péptidos marinhos na terapia oncológica..Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2017/12/06. Apresentação oral de trabalho. Pereira, H., Parámo, J., Silva, J., Gouveia, L., Barreira, L., Varela, J. (2017) Laboratory, pilot-scale and industrial production of Tetraselmis sp. CTP4: Growth performance, culture medium recirculation and harvest of biomass. . AlgaeEurope 2017, 5-7 Dec, Berlin, Germany..
2017/10/17. Apresentação oral de trabalho. Barreira, L., Rodrigues, M.J., Martins, A., Rauter, A.P., Neng, N.R., Nogueira, J.M.F., Varela, J., Custódio, L. (2015) Chemical Composition and in vitro Anti-diabetic Properties of the Medicinal Maritime Halophyte Polygonum maritimum. 2nd International Conference on Natural Products Utilization: From Plants to Pharmacy Shelf (ICNPU 2015). ICNPU (Plovdiv, Bulgária).
2012 - 2016. Orientação. Unravelling the pathways of antitumour action of different fractions of selected marine organisms and halophytes..Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2016 - 2016. Orientação. Farmacogenómica do Cancro da Mama.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2016 - 2016. Orientação. Aplicação de fitoterapia como terapêutica coadjuvante e preventiva de doenças inflamatórias intestinais: Colite Ulcerosa e Doença de Crohn..Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2016 - 2016. Orientação. Growth and analysis of microalgae for biotechnological applications.Biologia (Licenciatura/Bacharelato). Orientador.
2016 - 2016. Orientação. Comparative approach of molecular-based methodologies for the identification of biomedical relevant brown macroalgae of the Cystoseira genus..Biologia (Licenciatura/Bacharelato). Orientador.
2016/01/07. Apresentação oral de trabalho. Vizetto-Duarte C, Custódio L, Neng N, Nogueira JMF, Lago JHG, Morais TR, Bruno de Sousa C, Barreira L, Albericio F, Rauter AP and Varela J. (2016) Searching for bioactive compounds in brown algae.. COLACRO – XVI Congresso Latino-Americano de Cromatografia/Encontro Nacional de Cromatografia.
2015 - 2015. Orientação. Marine photosynthetic organisms from the Portuguese coast as sources of antitumoural compounds.Mestrado em Oncobiologia (Mestrado). Orientador.
2015 - 2015. Orientação. Exploitation of bioactive molecules in different streams of the downstream processing of wet microalgal biomass into biodiesel considering a biorefinery approach.Mestrado em Biologia Molecular e Microbiana (Mestrado). Orientador.
2015 - 2015. Orientação. Algae from the Portuguese coast as source of bioactive compounds..Biologia (Licenciatura/Bacharelato). Coorientador.
2015 - 2015. Orientação. Avaliação preliminar das propriedades físico-químicas do biodiesel produzido a partir de uma microalga autóctone da Ria Formosa..Biologia (Licenciatura/Bacharelato). Orientador.
2015 - 2015. Orientação. Incorporation of selenium on microalgae as supplement to rotifers and zebrafish.Mestrado em Aquacultura e Pescas (Mestrado). Coorientador.
2015/12/03. Apresentação oral de trabalho. Pereira H, Gangadhar K, Custódio L, Gouveia L, Barreira L, Varela J (2015) Biotechnological applications of a promising marine chlorophyte (Tetraselmis sp. CTP4). . AlgaeEurope, 1-3 Dec. Lisbon.
2015/09/15. Apresentação oral de trabalho. Vizetto-Duarte C, Custódio L, Lago JHG, Morais TR, de Sousa CB, Gangadhar KN, Barreira L, Albericio F, Rauter AP and Varela J. (2015) Cystoseira tamariscifolia as a potential biomedical source for antioxidant and anti- hepatocarcinoma compounds.. CQB Day – Centro de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Portugal. .
2015/05/26. Apresentação oral de trabalho. Bruno-de-Sousa C, Morais TR, Gangadhar KN, Conserva GA, Vizetto-Duarte C, Barreira L, Custódio L, Campino L, Passero LFD, Lago JHG, Varela J. (2015) Antileishmanial activity of compounds from Cystoseira baccata. . 38ª Reunião Anual da Sociedade Brasileira de Química. Sociedade Brasileira de Química (Águas de Lindóia, Brasil).
2011 - 2014. Orientação. SEAWEED AD—Anaerobic Digestion of Seaweed for Biofuel.FP7-PEOPLE-2010-IEF (Outra). Orientador.
2009 - 2014. Orientação. Regulation of iron homeostasis in cyanobacteria.Post-doc in project PTDC/BIA-MIC/101036/2008 (Outra). Coorientador.
2014 - 2014. Orientação. Effects of light quality supplied by light emitting diodes (LEDs) on microalgal production.Mestrado em Aquacultura e Pescas (Mestrado). Orientador.
2014 - 2014. Orientação. Estudo do efeito da salinidade e concentração de ferro no crescimento e conteúdo lipídico da estirpe de microalga CTP4.Mestrado em Biologia Marinha (Mestrado). Orientador.
2014 - 2014. Orientação. Physiology and biochemistry of the effect of abiotic stress on the autochthonous CTP4 strain, a candidate microalga for biofuel production in Algarve.Mestrado em Biologia Marinha (Mestrado). Coorientador.
2014 - 2014. Orientação. Antileishmanial Screening of Marine Natural Products Against Intracellular Leishmania Amastigotes. Coorientador.
2014 - 2014. Orientação. Sindrome de Hutchinson-Gilford: passado, presente e adordagens terapêuticas futuras.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2014 - 2014. Orientação. Pesquisa de biocompostos em extractos marinhos com potencial uso no tratamento da Doença de Alzheimer.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Coorientador.
2014 - 2014. Orientação. Organismos marinhos como fonte de compostos citotóxicos e antitumorais.Mestrado Integrado em Ciências Farmacêuticas (Mestrado). Orientador.
2014 - 2014. Orientação. Taxonomic Analyses Of The Genus Cystoseira C. Agardh, 1820 (Fucales, Phaeophyceae) Through Phylogenetic Inference Methods.Biologia (Licenciatura/Bacharelato). Orientador.
2014 - 2014. Orientação. Comparação de populações de Vibrio spp. cultiváveis associadas a esponjas, gorgónias e larvas de Sparus aurata.Biologia (Licenciatura/Bacharelato). Coorientador.
2014. Apresentação oral de trabalho. Rodrigues M. J., Varela J., Custódio L., Barreira L. (2014). In vitro anti-diabetic properties of different organs of two Juncaceae species.. Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research - GA 2014. Society of Medicinal Plant and Natural Product Research (Guimarães, Portugal).
2014. Apresentação oral de trabalho. Rodrigues M. J., Barreira L., Martins A., Rauter A. P., Neng N., Nogueira J., Varela J., Custódio L. (2014). Comparative evaluation of the polyphenolic composition of different organs of the medicinal halophyte Limonium algarvense.. 8th World Congress on Polyphenols Applications.
2014 - 2014. Participação em evento. Rodrigues, M.J., Soszynski, A., Varela, J., Barreira, L., Custódio, L. (2014). Antioxidant and neuroprotective potential of two halophytes from the Algarve coast. Congresso. 62nd International Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research - GA 2014.
2014. Apresentação oral de trabalho. Vizetto-Duarte, C.; Rodrigues, M.J.; Pereira, H.; Neng, N.; Nogueira, J.; Vasconcelos, H.; Barreira, L.; Custódio, L.; Rauter, A.P.; Albericio, F.; Varela, J. (2014). Antitumoural activity of Cystoseira species: insights into the mechanism of action.. 62nd International Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research - GA 2014. Society of Medicinal Plant and Natural Product Research (Guimarães, Portugal).
2014 - 2014. Participação em evento. Oliveira, M.; Bruno de Sousa, C.; Cortes, S.; Barreira, L.; Custódio, L.; Varela, J. (2014). Influence of the extraction method on the antiprotozoal activity of two Iberian Cystoseira species.. Congresso. 62nd International Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research - GA 2014.
2011 - 2013. Orientação. Biochemical characterization of anti-tumoural compounds present in selected halophytes.Post-doc (Outra). Orientador.
2009 - 2013. Orientação. Screening for biological activities from marine photosynthetic organisms.Post-doc - SFRH/BPD/65116/2009 (Outra). Orientador.
2013 - 2013. Orientação. Searching for biocompounds in marine natural extracts with potential use against acute lymphocytic leukemia (ALL).. Coorientador.
2013 - 2013. Orientação. Screening for biological activities with application in aquaculture in halophytes from the Algarve coastline. Coorientador.
2012 - 2012. Orientação. Evaluation of the antibiotic potential of extracts on marine algae and seagrasses. Evaluation of the antibiotic potential of extracts on marine algae and seagrasses (Mestrado). Coorientador.
2012 - 2012. Orientação. Searching for biocompounds in marine natural extracts with potential use in the prevention of cardiovascular disorders. Coorientador.
2012 - 2012. Orientação. Screening for lipid-hyperproducing microalgae to implement a pilot biodiesel production facility.Mestrado em Aquacultura e Pescas (Mestrado). Orientador.
2011 - 2011. Orientação. Searching for bioactive compounds from macroalgae with interest in aquaculture as immunostimulants. .EMBC (Mestrado). Coorientador.
2011 - 2011. Orientação. Compostos bioactivos de microalgas com interesse em aquacultura como imunoestimulantes, antioxidantes e antibióticos. . Coorientador.
2010 - 2010. Orientação. Study of the antioxidant and antitumoural activity in extracts of different marine microalgae.Biologia (Licenciatura/Bacharelato). Orientador.
2010 - 2010. Orientação. Study of the neuroprotective activity in extracts of different marine photosynthetic organisms (MPOs). Coorientador.
2010 - 2010. Orientação. Isolation and characterization of microalgae for the biotechnological production of biodiesel..Biologia (Licenciatura/Bacharelato). Orientador.
2010 - 2010. Orientação. Study of the antioxidant and antitumoural activity of extracts de Cladostephus spongiosus, Jania sp. e Cymodocea nodosa.. Coorientador.
2004 - 2009. Orientação. Isolation and characterization of the lycopene cyclase gene involved in the carotenoid biosynthetic pathway in the microalga Dunaliella salina..Programa Doutoral em Ciências do Mar e Ambiente (Doutoramento). Orientador.
2003 - 2008. Orientação. Isolation and characterization of regulatory and biosynthetic genes involved in carotenogenesis in the microalga Dunaliella salina. . Orientador.
2006 - 2006. Orientação. Expression patterns of Lcy, an enzyme involved in the carotenoid biosynthetic pathway of Dunaliella salina (Teod.)..EMBC (Mestrado). Orientador.
2004 - 2004. Organização de evento. Congresso Nacional de Bioquímica (2004). Sociedade Portuguesa de Bioquímica.
2004 - 2004. Orientação. Isolation of antioxidant compounds from Cecropia leucocoma, Cecropiaceae, a plant from the Amazon’s rain forest.. Coorientador.
2001 - 2003. Orientação. Characterization of a subtractive cDNA library from Dunaliella salina CCAP 19/30 under salt stress..Post doc - BPD/3579/2000 (Outra). Orientador.
2003 - 2003. Orientação. Comparison of three photobioreactors for the production of astaxanthin by Haematococcus pluvialis (Chlorophyceae). . Orientador.
2002 - 2002. Orientação. Development of methodologies for the optimization of the carotenogenic process in Dunaliella salina.. Orientador.
1993 - 1993. Organização de evento. Stress Response of Yeast Meeting (1993). Vrije Universiteit Amsterdam.
Projetos
Projetos
2019/10/01 - Presente. ProFuture - MICROALGAE PROTEIN INGREDIENTS FOR THE FOOD AND FEED OF THE FUTURE, Horizon 2020. Investigador.
2020/10/26 - 2022/10/25. EEA.BG.CALL1.032.2019 ALGACYCLE - "Valorisation of greenhouse effluents with microalgae:Sustainable aquafeeds and biostimulants from drain water". Investigador.
2021/06/01 - Presente. ALGAE4IBD –FROM NATURE TO BEDSIDE- ALGAE BASED BIO COMPOUND FOR PREVENTION AND TREATMENT OF INFLAMMATION, PAIN AND IBD, Horizon 2020 Framework Programme (H2020). Investigador. Centro de Ciências do Mar; Laboratório Colaborativo de Tecnologias e Produtos Verdes de Oceano.
2022/06/01 - Presente. Vertical Algas - Subroject SP1c - IMPROVEMENT OF ALGAL BIOMASS USING BIOPROSPECTION AND ALGAE-ASSOCIATED MICROBIOMES, PRR. Investigador responsável. Centro de Ciências do Mar.
2022/02/01 - Presente. REALM - Reusing effluents from agriculture to unlock the potential of microalgae, HORIZON-CL6-2021-CIRCBIO-01-09. Investigador. Laboratório Colaborativo de Tecnologias e Produtos Verdes de Oceano.
2021 - Presente. ALLARVAE - Novas formulações de microalgas para larvicultura marinha, Programa Operacional Regional do Algarve. Investigador. Universidade do Algarve.
2021 - Presente. ALGAESOLUTIONS - Solutions to improve growth, induce high value metabolites and detect contaminants to produce novel algal products, Programa Operacional Regional do Algarve. Investigador. Agência Nacional de Inovação SA; Comissão de Coordenação e Desenvolvimento Regional do Algarve.
2020/01/01 - 2021/12/31. ZEBRABLOOM - Desenvolvimento de produtos comerciais formulados com microalgas para o enriquecimento de presas vivas de peixe-zebra. , Portugal2020. Investigador. Universidade do Algarve - Campus de Gambelas.
2018/09/01 - 2021/08/31. GREENTREAT: AN INTEGRATED, SUSTAINABLE PROCESS FOR THE TERTIARY TREATMENT OF URBAN WASTEWATER USING MICROALGAE IN THE ALGARVE REGION, Projetos de I&D em todas as áreas. Investigador. Centro de Ciências do Mar.
2021/01/01 - Presente. PERFORMALGAE - Establishment of highly performant industrial microalgal cultures for the production of biostimulants and functional foods, Portugal 2020. Investigador. Laboratório Colaborativo de Tecnologias e Produtos Verdes de Oceano; Universidade do Algarve.
2016/01/01 - 2018/12/31. XtremeGourmet – Plantas EXtremófilas na Cozinha Gourmet, COMPETE 2020. Investigador. Universidade do Algarve - Campus de Gambelas.
2018/01/01 - Presente. ALGAVALOR - MicroALGAs: produção integrada e VALORização da biomassa e das suas diversas aplicações, CRESC ALGARVE 2020. Investigador. Universidade do Algarve - Campus de Gambelas.
2017/05/03 - Presente. ALGARED+ - RED transfronteriza para el desarrollo de productos innovadores con microALGAs, POCTEP - INTERREG V-A España-Portugal . Investigador responsável. Universidade do Algarve - Campus de Gambelas.
2017/01/01 - Presente. ALGACO2 - Industrial cultivation of microalgae as a green strategy for atmospheric CO2 sequestration. O-C-TEC-01/17-Research Contract with CMP-Secil, Research Contract. Investigador responsável. Centro de Ciências do Mar.
2013/07/01 - 2015/12/31. The regulation of photosynthesis in cyanobacteria: A systems biology approach, 3599-PPCDT. Centro de Ciências do Mar.
2013/05/01 - 2015/08/31. XTREMEBIO - Halophytes: a precious resource of nutritional elements and bioactive compounds, 3599-PPCDT. Investigador. Centro de Ciências do Mar.
2011/09/01 - 2013/08/31. SEAWEED AD—Anaerobic Digestion of Seaweed for Biofuels. , FP7-PIEF - Marie Curie for Senior Scientists. Investigador responsável. Centro de Ciências do Mar.
2010/01/01 - 2013/06/30. CYANO - Regulation of iron homeostasis in cyanobacteria, 3599-PPCDT. Investigador. Centro de Ciências do Mar.
2010/01/04 - 2013/04/30. SEABIOMED - Marine photosynthetic organisms of the Algarve coast with biomedical applications, 3599-PPCDT. Investigador. Centro de Ciências do Mar.
2011/04/01 - 2013/03/31. SABA-1. Screening for lipid hyper-producers species in Saudi Arabia coastal waters for Biofuel production from micro-Algae, KAUST Funding. Investigador responsável. Centro de Ciências do Mar.
2007/01/01 - 2009/12/31. Botryofuel – Microalgas hiperprodutoras de hidrocarbonetos, POCI. Investigador. Centro de Ciências do Mar.
2007/01/01 - 2008/12/31. NITEC-GENTEC - Stimulating systems for the creation of research & technological development nuclei in entrepreneurial sector., NITEC-GENTEC. Investigador. Centro de Ciências do Mar.
2005/01/01 - 2008/12/31. SAL - Salinas do Atlântico. Recovery of the identity of Atlantic salt pans (salinas). Recovery and promotion of the biological, economical, and cultural potential of humid coastal areas, INTERREG IIIB - Atlantic. Investigador. Universidade do Algarve - Campus de Gambelas.
2002/01/01 - 2005/12/31. ALGINET - Microalgae as cell factories for chemical and biochemical productions.. Investigador. Centro de Ciências do Mar.
2002/03/01 - 2005/02/28. OVERCAROTEN - Isolation of carotenoid-overproducing strains of Dunaliella salina, PDTCM-99. Investigador responsável. Centro de Ciências do Mar.
2000/01/01 - 2002/12/30. ALGSTRESS - Molecular responses to water stress of algae with elevated tolerance to high salinity and desiccation, PRAXIS. Investigador. Centro de Ciências do Mar.
1999 - 2001. NOVALGAS, New applications for concentrated microalgae. Investigador. Universidade do Algarve.
1998 - 1998. Utilization of biotechnological processes for microalgae valorization, PRAXIS XXI. Investigador responsável. Centro de Ciências do Mar.
Produções
Matinha-Cardoso, Jorge; Santos, Tamára; Pereira, Hugo; Varela, João; Tamagnini, Paula; Mota, Rita. 2023. "Pilot scale production of Crocosphaera chwakensis CCY0110 and evaluation of its biomass nutritional potential". Algal Research, 69. https://doi.org/10.1016/j.algal.2022.102939
Bombo, Gabriel; Cristofoli, Nathana L.; Santos, Tamára F.; Schüler, Lisa; Maia, Inês B.; Pereira, Hugo; Barreira, Luísa; Varela, João. 2023. "Dunaliella viridis TAV01: A Halotolerant, Protein-Rich Microalga from the Algarve Coast". Applied Sciences, 13 (4). https://doi.org/10.3390/app13042146
Cristofoli, Nathana L.; Lima, Alexandre R.; Rosa da Costa, Ana M.; Evtyugin, Dmitry; Silva, Carlos; Varela, João; Vieira, Margarida C.. 2023. "Structural characterization of exopolysaccharides obtained from Porphyridium cruentum exhausted culture medium". Food and Bioproducts Processing, 138: 162-171. https://doi.org/10.1016/j.fbp.2023.02.001
Maia, Inês B.; Carneiro, Mariana; Magina, Tânia; Malcata, F. Xavier; Otero, Ana; Navalho, João; Varela, João; Pereira, Hugo. 2022. "Diel biochemical and photosynthetic monitorization of Skeletonema costatum and Phaeodactylum tricornutum grown in outdoor pilot-scale flat panel photobioreactors". Journal of Biotechnology, 343: 110-119. https://doi.org/10.1016/j.jbiotec.2021.11.008
Carneiro, M.; Maia, I.B.; Cunha, P.; Guerra, I.; Magina, T.; Santos, T.; Schulze, P.S.C.; et al. 2022. "Effects of LED lighting on Nannochloropsis oceanica grown in outdoor raceway ponds". Algal Research, 64. https://doi.org/10.1016/j.algal.2022.102685
Morais, Etiele Greque de; Amaro Marques, José Carlos; Cerqueira, Paulo Ricardo; Dimas, Cláudia; Sousa, Vânia Serrão; Gomes, Nuno; Ribau Teixeira, Margarida; et al. 2022. "Tertiary urban wastewater treatment with microalgae natural consortia in novel pilot photobioreactors". Journal of Cleaner Production, 378. https://doi.org/10.1016/j.jclepro.2022.134521
Barros, Raúl; Raposo, Sara; Morais, Etiele G.; Rodrigues, Brígida; Afonso, Valdemira; Gonçalves, Pedro; Marques, José; et al. 2022. "Biogas Production from Microalgal Biomass Produced in the Tertiary Treatment of Urban Wastewater: Assessment of Seasonal Variations". Energies, 15 (15). https://doi.org/10.3390/en15155713
Trovão, Mafalda; Schüler, Lisa M.; Machado, Adriana; Bombo, Gabriel; Navalho, Sofia; Barros, Ana; Pereira, Hugo; et al. 2022. "Random Mutagenesis as a Promising Tool for Microalgal Strain Improvement towards Industrial Production". Marine Drugs, 20 (7). https://doi.org/10.3390/md20070440
Mendes, Madalena; Navalho, Sofia; Ferreira, Alice; Paulino, Cristina; Figueiredo, Daniel; Silva, Daniel; Gao, Fengzheng; et al. 2022. "Algae as Food in Europe: An Overview of Species Diversity and Their Application". Foods, 11 (13). https://doi.org/10.3390/foods11131871
Schmid, Benjamin; Navalho, Sofia; Schulze, Peter S. C.; Van De Walle, Simon; Van Royen, Geert; Schüler, Lisa M.; Maia, Inês B.; et al. 2022. "Drying Microalgae Using an Industrial Solar Dryer: A Biomass Quality Assessment". Foods, 11 (13). https://doi.org/10.3390/foods11131873
Silva, Mélanie; Kamberovic, Farah; Uota, Sisay Tesema; Kovan, Ismael-Mohammed; Viegas, Carla S. B.; Simes, Dina C.; Gangadhar, Katkam N.; Varela, João; Barreira, Luísa. 2022. "Microalgae as Potential Sources of Bioactive Compounds for Functional Foods and Pharmaceuticals". Applied Sciences, 12 (12). https://doi.org/10.3390/app12125877
Schmid, Benjamin; Coelho, Luísa; Schulze, Peter S.C.; Pereira, Hugo; Santos, Tamára; Maia, Inês B.; Reis, Mário; Varela, João. 2022. "Antifungal properties of aqueous microalgal extracts". Bioresource Technology Reports, 18. https://doi.org/10.1016/j.biteb.2022.101096
Couto, Daniela; Conde, Tiago A.; Melo, Tânia; Neves, Bruna; Costa, Margarida; Cunha, Pedro; Guerra, Inês; et al. 2022. "Effects of outdoor and indoor cultivation on the polar lipid composition and antioxidant activity of Nannochloropsis oceanica and Nannochloropsis limnetica: A lipidomics perspective". Algal Research, 64. https://doi.org/10.1016/j.algal.2022.102718
Bastos, Carolina R. V.; Maia, Inês B.; Pereira, Hugo; Navalho, João; Varela, João C. S.. 2022. "Optimisation of Biomass Production and Nutritional Value of Two Marine Diatoms (Bacillariophyceae), Skeletonema costatum and Chaetoceros calcitrans". Biology, 11 (4). https://doi.org/10.3390/biology11040594
Letras, P.; Oliveira, S.; Varela, J.; Nunes, M.C.; Raymundo, A.. 2022. "3D printed gluten-free cereal snack with incorporation of Spirulina (Arthrospira platensis) and/or Chlorella vulgaris". Algal Research, 68. https://doi.org/10.1016/j.algal.2022.102863
Lima, Serena; Schulze, Peter S.C.; Schüler, Lisa M.; Rautenberger, Ralf; Morales-Sánchez, Daniela; Santos, Tamára F.; Pereira, Hugo; et al. 2021. "Flashing light emitting diodes (LEDs) induce proteins, polyunsaturated fatty acids and pigments in three microalgae". Journal of Biotechnology, 325: 15-24. https://doi.org/10.1016/j.jbiotec.2020.11.019
Guerra, Inês; Pereira, Hugo; Costa, Margarida; Silva, Joana T.; Santos, Tamára; Varela, João; Mateus, Marília; Silva, Joana. 2021. "Operation Regimes: A Comparison Based on Nannochloropsis oceanica Biomass and Lipid Productivity". Energies, 14 (6). https://doi.org/10.3390/en14061542
Schüler, Lisa M.; Bombo, Gabriel; Duarte, Paulo; Santos, Tamára F.; Maia, Inês B.; Pinheiro, Filipa; Marques, José; et al. 2021. "Carotenoid biosynthetic gene expression, pigment and n-3 fatty acid contents in carotenoid-rich Tetraselmis striata CTP4 strains under heat stress combined with high light". Bioresource Technology, 337. https://doi.org/10.1016/j.biortech.2021.125385
Carneiro, Mariana; Chini Zittelli, Graziella; Cicchi, Bernardo; Touloupakis, Eleftherios; Faraloni, Cecilia; Maia, Inês B.; Pereira, Hugo; et al. 2021. "In situ monitoring of chlorophyll
a
fluorescence in
Nannochloropsis oceanica
cultures to assess photochemical changes and the onset of lipid accumulation during nitrogen deprivation". Biotechnology and Bioengineering. https://doi.org/10.1002/bit.27906
a
fluorescence in
Nannochloropsis oceanica
cultures to assess photochemical changes and the onset of lipid accumulation during nitrogen deprivation". Biotechnology and Bioengineering. https://doi.org/10.1002/bit.27906
Carneiro, Mariana; Ranglová, Karolína; Lakatos, Gergely Erno; Câmara Manoel, João Artur; Grivalský, Tomáš; Kozhan, Daniyar Malikuly; Toribio, Ana; et al. 2021. "Growth and bioactivity of two chlorophyte (Chlorella and Scenedesmus) strains co-cultured outdoors in two different thin-layer units using municipal wastewater as a nutrient source". Algal Research, 56. https://doi.org/10.1016/j.algal.2021.102299
Lima, Alexandre R.; Gama, Florinda; Castañeda-Loaiza, Viana; Costa, Camila; Schüler, Lisa M.; Santos, Tamára; Salazar, Miguel; et al. 2021. "Nutritional and Functional Evaluation of Inula crithmoides and Mesembryanthemum nodiflorum Grown in Different Salinities for Human Consumption". Molecules, 26 (15). https://doi.org/10.3390/molecules26154543
Morais, Etiele G.; Cristofoli, Nathana L.; Maia, Inês B.; Magina, Tânia; Cerqueira, Paulo R.; Teixeira, Margarida Ribau; Varela, João; Barreira, Luísa; Gouveia, Luísa. 2021. "Microalgal Systems for Wastewater Treatment: Technological Trends and Challenges towards Waste Recovery". Energies, 14 (23). https://doi.org/10.3390/en14238112
Pereira, Hugo; Sardinha, Manuel; Santos, Tamára; Gouveia, Luísa; Barreira, Luísa; Dias, Jorge; Varela, João. 2020. "Incorporation of defatted microalgal biomass (Tetraselmis sp. CTP4) at the expense of soybean meal as a feed ingredient for juvenile gilthead seabream (Sparus aurata)". Algal Research, 47. https://doi.org/10.1016/j.algal.2020.101869
Cunha, Pedro; Pereira, Hugo; Costa, Margarida; Pereira, João; Silva, Joana T.; Fernandes, Nuno; Varela, João; Silva, Joana; Simões, Manuel. 2020. "Nannochloropsis oceanica Cultivation in Pilot-Scale Raceway Ponds—From Design to Cultivation". Applied Sciences, 10 (5). https://doi.org/10.3390/app10051725
Schüler, Lisa M.; Santos, Tamára; Pereira, Hugo; Duarte, Paulo; Katkam, N. Gangadhar; Florindo, Cláudia; Schulze, Peter S.C.; Barreira, Luísa; Varela, João C.S.. 2020. "Improved production of lutein and ß-carotene by thermal and light intensity upshifts in the marine microalga Tetraselmis sp. CTP4". Algal Research, 45. https://doi.org/10.1016/j.algal.2019.101732
Schüler, Lisa M.; Gangadhar, Katkam N.; Duarte, Paulo; Placines, Chloé; Molina-Márquez, Ana María; Léon-Bañares, Rosa; Sousa, Vânia S.; Varela, João; Barreira, Luísa. 2020. "Improvement of carotenoid extraction from a recently isolated, robust microalga, Tetraselmis sp. CTP4 (chlorophyta)". Bioprocess and Biosystems Engineering. https://doi.org/10.1007/s00449-019-02273-9
Varela, João. 2020. "Isolation and characterization of novel Chlorella vulgaris mutants with low chlorophyll and improved protein contents for food applications.". Applied Sciences.
Trovão, Mafalda; Pereira, Hugo; Costa, Margarida; Machado, Adriana; Barros, Ana; Soares, Maria; Carvalho, Bernardo; Silva, Joana; Varela, João. 2020. "Lab-Scale Optimization of Aurantiochytrium sp. Culture Medium for Improved Growth and DHA Production". Applied Sciences, 10 (7). https://doi.org/10.3390/app10072500
Varela, João. 2020. "Isolation, identification and biotechnological applications of a novel, robust, free-living Chlorococcum (Oophila) amblystomatis strain isolated from a local pond.". Applied Sciences.
Lima, Alexandre R.; Castañeda-Loaiza, Viana; Salazar, Miguel; Nunes, Carla; Quintas, Célia; Gama, Florinda; Pestana, Maribela; et al. 2020. "Influence of cultivation salinity in the nutritional composition, antioxidant capacity and microbial quality of Salicornia ramosissima commercially produced in soilless systems". Food Chemistry, 333. https://doi.org/10.1016/j.foodchem.2020.127525
Castañeda-Loaiza, Viana; Oliveira, Marta; Santos, Tamára; Schüler, Lisa; Lima, Alexandre R.; Gama, Florinda; Salazar, Miguel; et al. 2020. "Wild vs cultivated halophytes: Nutritional and functional differences". Food Chemistry, 333. https://doi.org/10.1016/j.foodchem.2020.127536
Gangadhar, Katkam N.; Rodrigues, Maria João; Pereira, Hugo; Gaspar, Helena; Malcata, F. Xavier; Barreira, Luísa; Varela, João. 2020. "Anti-Hepatocellular Carcinoma (HepG2) Activities of Monoterpene Hydroxy Lactones Isolated from the Marine Microalga Tisochrysis Lutea". Marine Drugs, 18 (11). https://doi.org/10.3390/md18110567
Gómez-Villegas, Patricia; Vigara, Javier; Vila, Marta; Varela, João; Barreira, Luísa; Léon, Rosa. 2020. "Antioxidant, Antimicrobial, and Bioactive Potential of Two New Haloarchaeal Strains Isolated from Odiel Salterns (Southwest Spain)". Biology, 9 (9). https://doi.org/10.3390/biology9090298
Carneiro, M.; Cicchi, B.; Maia, I.B.; Pereira, H.; Zittelli, G. Chini; Varela, J.; Malcata, F. Xavier; Torzillo, G.. 2020. "Effect of temperature on growth, photosynthesis and biochemical composition of Nannochloropsis oceanica, grown outdoors in tubular photobioreactors". Algal Research, 49. https://doi.org/10.1016/j.algal.2020.101923
Machado, Adriana; Pereira, Hugo; Costa, Margarida; Santos, Tamára; Carvalho, Bernardo; Soares, Maria; Quelhas, Pedro; et al. 2020. "Development of an Organic Culture Medium for Autotrophic Production of Chlorella vulgaris Biomass". Applied Sciences, 10 (6). https://doi.org/10.3390/app10062156
Varela, João. "Chlorococcum amblystomatis (F.D.Lambert ex Wille) N.Correia, J.Varela & Leonel Pereira, comb. nov. (Chlorococcaceae)". Notulae algarum, 138 (2020): 1-2. https://notulaealgarum.org/2020/documents/Notulae%20Algarum%20No.%20138.pdf
Pereira, Hugo; Silva, Joana; Santos, Tamára; Gangadhar, Katkam N.; Raposo, Ana; Nunes, Cláudia; Coimbra, Manuel A.; et al. 2019. "Nutritional Potential and Toxicological Evaluation of Tetraselmis sp. CTP4 Microalgal Biomass Produced in Industrial Photobioreactors". Molecules, 24 (17). https://doi.org/10.3390/molecules24173192
Trovão, Mafalda; Pereira, Hugo; Silva, Joana; Páramo, Jaime; Quelhas, Pedro; Santos, Tamára; Silva, Joana T.; et al. 2019. "Growth performance, biochemical composition and sedimentation velocity of Tetraselmis sp. CTP4 under different salinities using low-cost lab- and pilot-scale systems". Heliyon, 5 (5). https://doi.org/10.1016/j.heliyon.2019.e01553
Barros, A.; Pereira, H.; Campos, J.; Marques, A.; Varela, J.; Silva, J.. 2019. "Heterotrophy as a tool to overcome the long and costly autotrophic scale-up process for large scale production of microalgae". Scientific Reports, 9 (1). https://doi.org/10.1038/s41598-019-50206-z
Quelhas, Pedro M.; Trovão, Mafalda; Silva, Joana T.; Machado, Adriana; Santos, Tamára; Pereira, Hugo; Varela, João; Simões, Manuel; Silva, Joana L.. 2019. "Industrial production of Phaeodactylum tricornutum for CO2 mitigation: biomass productivity and photosynthetic efficiency using photobioreactors of different volumes". Journal of Applied Phycology, 31 (4): 2187-2196. https://doi.org/10.1007/s10811-019-1750-0
Cardoso, C.; Pereira, H.; Franca, J.; Matos, J.; Monteiro, I.; Pousão-Ferreira, P.; Gomes, A.; et al. 2019. "Lipid composition and some bioactivities of 3 newly isolated microalgae (Tetraselmis sp. IMP3, Tetraselmis sp. CTP4, and Skeletonema sp.)". Aquaculture International, 28 (2): 711-727. https://doi.org/10.1007/s10499-019-00489-w
Bruno de Sousa, Carolina; Cox, Cymon J.; Brito, Luís; Pavão, Maria Madalena; Pereira, Hugo; Ferreira, Ana; Ginja, Catarina; et al. 2019. "Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences". PLOS ONE, 14 (1). https://doi.org/10.1371/journal.pone.0210143
Baessa, M.; Rodrigues, M.J.; Pereira, C.; Santos, T.; da Rosa Neng, N.; Nogueira, J.M.F.; Barreira, L.; et al. 2019. "A comparative study of the in vitro enzyme inhibitory and antioxidant activities of Butea monosperma (Lam.) Taub. and Sesbania grandiflora (L.) Poiret from Pakistan: New sources of natural products for public health problems". South African Journal of Botany, 120: 146-156. https://doi.org/10.1016/j.sajb.2018.04.006
Rodrigues, M.J.; Oliveira, M.; Neves, V.; Ovelheiro, A.; Pereira, C.A.; Neng, N.R.; Nogueira, J.M.F.; et al. 2019. "Coupling sea lavender (Limonium algarvense Erben) and green tea (Camellia sinensis (L.) Kuntze) to produce an innovative herbal beverage with enhanced enzymatic inhibitory properties". South African Journal of Botany, 120: 87-94. https://doi.org/10.1016/j.sajb.2017.12.003
Varela, João. 2018. "Fatty acid composition and nutraceutical perspectives of brown seaweeds from the Atlantic coast of Morocco". International Food Research Journal, 25 (4): 1520-1527. http://www.ifrj.upm.edu.my/25%20(04)%202018/(27).pdf
Rodrigues, Maria João; Vizetto-Duarte, Catarina; Gangadhar, Katkam N.; Zengin, Gokhan; Mollica, Adriano; Varela, João; Barreira, Luísa; Custódio, Luísa. 2018. "In vitro and in silico approaches to unveil the mechanisms underlying the cytotoxic effect of juncunol on human hepatocarcinoma cells". Pharmacological Reports, 70 (5): 896-899. https://doi.org/10.1016/j.pharep.2018.02.001
Ripol, Andrea; Cardoso, Carlos; Afonso, Cláudia; Varela, João; Quental-Ferreira, Hugo; Pousão-Ferreira, Pedro; Bandarra, Narcisa M.. 2018. "Composition, Anti-inflammatory Activity, and Bioaccessibility of Green Seaweeds from Fish Pond Aquaculture". Natural Product Communications, 13 (5). https://doi.org/10.1177/1934578x1801300521
Pereira, Hugo; Páramo, Jaime; Silva, Joana; Marques, Ana; Barros, Ana; Maurício, Dinis; Santos, Tamára; et al. 2018. "Scale-up and large-scale production of Tetraselmis sp. CTP4 (Chlorophyta) for CO2 mitigation: from an agar plate to 100-m3 industrial photobioreactors". Scientific Reports, 8 (1). https://doi.org/10.1038/s41598-018-23340-3
Pereira, Catarina Guerreiro; Barreira, Luísa; Bijttebier, Sebastiaan; Pieters, Luc; Marques, Cátia; Santos, Tamára F.; Rodrigues, Maria João; Varela, João; Custódio, Luísa. 2018. "Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp. maritima: from traditional remedies to prospective products". Scientific Reports, 8 (1). https://doi.org/10.1038/s41598-018-23038-6
Pereira, Hugo; Schulze, Peter S.C.; Schüler, Lisa Maylin; Santos, Tamára; Barreira, Luísa; Varela, João. 2018. "Fluorescence activated cell-sorting principles and applications in microalgal biotechnology". Algal Research, 30: 113-120. https://doi.org/10.1016/j.algal.2017.12.013
Afonso, C.; Cardoso, C.; Ripol, A.; Varela, J.; Quental-Ferreira, H.; Pousão-Ferreira, P.; Ventura, M.S.; et al. 2018. "Composition and bioaccessibility of elements in green seaweeds from fish pond aquaculture". Food Research International, 105: 271-277. https://doi.org/10.1016/j.foodres.2017.11.015
Rodrigues, Maria João; Slusarczyk, Sylwester; Pecio, Lukasz; Matkowski, Adam; Salmas, Ramin Ekhteiari; Durdagi, Serdar; Pereira, Catarina; et al. 2018. "In vitro and in silico approaches to appraise Polygonum maritimum L. as a source of innovative products with anti-ageing potential". Industrial Crops and Products, 111: 391-399. https://doi.org/10.1016/j.indcrop.2017.10.046
Schulze, Peter S.C.; Guerra, Rui; Pereira, Hugo; Schüler, Lisa M.; Varela, João C.S.. 2017. "Flashing LEDs for Microalgal Production". Trends in Biotechnology, 35 (11): 1088-1101. https://doi.org/10.1016/j.tibtech.2017.07.011
Bruno de Sousa, Carolina; Gangadhar, Katkam N.; Macridachis, Jorge; Pavão, Madalena; Morais, Thiago R.; Campino, Lenea; Varela, João; Lago, João Henrique G.. 2017. "Cystoseira algae (Fucaceae): update on their chemical entities and biological activities". Tetrahedron: Asymmetry, 28 (11): 1486-1505. https://doi.org/10.1016/j.tetasy.2017.10.014
Braga, Tiago; Rodrigues, Maria João; Pereira, Hugo; Varela, João; Barreira, Luísa; González-Wangüemert, Mercedes; Custódio, Luísa. 2017. "Bursatella leachii from Mar Menor as a Source of Bioactive Molecules: Preliminary Evaluation of the Nutritional Profile,In VitroBiological Activities, and Fatty Acids Contents". Journal of Aquatic Food Product Technology, 26 (10): 1337-1350. https://doi.org/10.1080/10498850.2017.1392670
Cardoso, Carlos; Ripol, Andrea; Afonso, Cláudia; Freire, Margarida; Varela, João; Quental-Ferreira, Hugo; Pousão-Ferreira, Pedro; Bandarra, Narcisa. 2017. "Fatty acid profiles of the main lipid classes of green seaweeds from fish pond aquaculture". Food Science & Nutrition, 5 (6): 1186-1194. https://doi.org/10.1002/fsn3.511
Schüler, Lisa M.; Schulze, Peter S.C.; Pereira, Hugo; Barreira, Luísa; León, Rosa; Varela, João. 2017. "Trends and strategies to enhance triacylglycerols and high-value compounds in microalgae". Algal Research, 25: 263-273. https://doi.org/10.1016/j.algal.2017.05.025
Schulze, Peter S.C.; Carvalho, Carolina F.M.; Pereira, Hugo; Gangadhar, Katkam N.; Schüler, Lisa M.; Santos, Tamára F.; Varela, João C.S.; Barreira, Luísa. 2017. "Urban wastewater treatment by Tetraselmis sp. CTP4 (Chlorophyta)". Bioresource Technology, 223: 175-183. https://doi.org/10.1016/j.biortech.2016.10.027
Roggatz, Christina C; González-Wangüemert, Mercedes; Pereira, Hugo; Vizetto-Duarte, Catarina; Rodrigues, Maria João; Barreira, Luísa; da Silva, Manuela Moreira; Varela, João; Custódio, Luísa. 2017. "A first glance into the nutritional properties of the sea cucumber Parastichopus regalis from the Mediterranean Sea (SE Spain)". Natural Product Research, 32 (1): 116-120. https://doi.org/10.1080/14786419.2017.1331224
Oliveira, Marta; João Rodrigues, Maria; Pereira, Catarina; Neto, Rubens Lima do Monte; Junior, Policarpo Ademar Santos; Neng, Nuno da Rosa; Nogueira, José Manuel Florêncio; et al. 2017. "First report of the in vitro antileishmanial properties of extremophile plants from the Algarve Coast". Natural Product Research, 32 (5): 600-604. https://doi.org/10.1080/14786419.2017.1326489
Barreira, Luísa; Resek, Eva; Rodrigues, Maria João; Rocha, Maria Isabel; Pereira, Hugo; Bandarra, Narcisa; da Silva, Manuela Moreira; Varela, João; Custódio, Luísa. 2017. "Halophytes: Gourmet food with nutritional health benefits?". Journal of Food Composition and Analysis, 59: 35-42. https://doi.org/10.1016/j.jfca.2017.02.003
Bruno de Sousa, Carolina; Gangadhar, Katkam N.; Morais, Thiago R.; Conserva, Geanne A.A.; Vizetto-Duarte, Catarina; Pereira, Hugo; Laurenti, Márcia D.; et al. 2017. "Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata". Experimental Parasitology, 174: 1-9. https://doi.org/10.1016/j.exppara.2017.01.002
Rodrigues, Maria João; Custódio, Luísa; Lopes, Andreia; Oliveira, Marta; Neng, Nuno R.; Nogueira, José M. F.; Martins, Alice; et al. 2017. "Unlocking the in vitro anti-inflammatory and antidiabetic potential of Polygonum maritimum". Pharmaceutical Biology, 55 (1): 1348-1357. https://doi.org/10.1080/13880209.2017.1301493
Pereira, Catarina Guerreiro; Barreira, Luísa; Bijttebier, Sebastiaan; Pieters, Luc; Neves, Vanessa; Rodrigues, Maria João; Rivas, Ricardo; Varela, João; Custódio, Luísa. 2017. "Chemical profiling of infusions and decoctions of Helichrysum italicum subsp. picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis)". Journal of Pharmaceutical and Biomedical Analysis, 145: 593-603. https://doi.org/10.1016/j.jpba.2017.07.007
Rocha, M.I.; Rodrigues, M.J.; Pereira, C.; Pereira, H.; da Silva, M.M.; Neng, N. da Rosa; Nogueira, J.M.F.; et al. 2017. "Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa". South African Journal of Botany, 111: 222-231. https://doi.org/10.1016/j.sajb.2017.03.036
Gangadhar, Katkam N.; Pereira, Hugo; Rodrigues, Maria João; Custódio, Luísa; Barreira, Luísa; Malcata, F. Xavier; Varela, João. 2016. "Microalgae-based unsaponifiable matter as source of natural antioxidants and metal chelators to enhance the value of wet Tetraselmis chuii biomass". Open Chemistry, 14 (1). https://doi.org/10.1515/chem-2016-0029
Lopes, Andreia; Rodrigues, Maria João; Pereira, Catarina; Oliveira, Marta; Barreira, Luísa; Varela, João; Trampetti, Francesca; Custódio, Luísa. 2016. "Natural products from extreme marine environments: Searching for potential industrial uses within extremophile plants". Industrial Crops and Products, 94: 299-307. https://doi.org/10.1016/j.indcrop.2016.08.040
Vizetto-Duarte, Catarina; Custódio, Luísa; Barreira, Luísa; Moreira da Silva, Manuela; P. Rauter, Amélia; Albericio, Fernando; Varela, João. 2016. "Proximate biochemical composition and mineral content of edible species from the genus Cystoseira in Portugal". Botanica Marina, 0 (0). https://doi.org/10.1515/bot-2016-0014
Pereira, C. G.; Custódio, L.; Rodrigues, M. J.; Neng, N. R.; Nogueira, J. M. F.; Carlier, J.; Costa, M. C.; Varela, J.; Barreira, L.. 2016. "Profiling of antioxidant potential and phytoconstituents of Plantago coronopus". Brazilian Journal of Biology, 77 (3): 632-641. https://doi.org/10.1590/1519-6984.02416
Oliveira, Marta; Barreira, Luísa; Gangadhar, Katkam N.; Rodrigues, Maria João; Santos, Tamára; Varela, João; Custódio, Luísa. 2016. "Natural products from marine invertebrates against Leishmania parasites: a comprehensive review". Phytochemistry Reviews, 15 (4): 663-697. https://doi.org/10.1007/s11101-016-9455-3
Custódio, Luísa; Silvestre, Laura; Rocha, Maria Isabel; Rodrigues, Maria João; Vizetto-Duarte, Catarina; Pereira, Hugo; Barreira, Luísa; Varela, João. 2016. "Methanol extracts from Cystoseira tamariscifolia and Cystoseira nodicaulis are able to inhibit cholinesterases and protect a human dopaminergic cell line from hydrogen peroxide-induced cytotoxicity". Pharmaceutical Biology, 54 (9): 1687-1696. https://doi.org/10.3109/13880209.2015.1123278
Rodrigues, Maria João; Neves, Vanessa; Martins, Alice; Rauter, Amélia P.; Neng, Nuno R.; Nogueira, José M.F.; Varela, João; Barreira, Luísa; Custódio, Luísa. 2016. "In vitro antioxidant and anti-inflammatory properties of Limonium algarvense flowers’ infusions and decoctions: A comparison with green tea (Camellia sinensis)". Food Chemistry, 200: 322-329. https://doi.org/10.1016/j.foodchem.2016.01.048
Vizetto-Duarte, Catarina; Custódio, Luísa; Acosta, Gerardo; Lago, João H.G.; Morais, Thiago R.; Bruno de Sousa, Carolina; Gangadhar, Katkam N.; et al. 2016. "Can macroalgae provide promising anti-tumoral compounds? A closer look atCystoseira tamariscifoliaas a source for antioxidant and anti-hepatocarcinoma compounds". PeerJ, 4. https://doi.org/10.7717/peerj.1704
Vizetto-Duarte, Catarina; Custódio, Luísa; Gangadhar, Katkam N.; Lago, João Henrique G.; Dias, Catarina; Matos, Ana Marta; Neng, Nuno; et al. 2016. "Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage". Phytomedicine, 23 (5): 550-557. https://doi.org/10.1016/j.phymed.2016.02.008
Schulze, Peter S.C.; Pereira, Hugo G.C.; Santos, Tamára F.C.; Schueler, Lisa; Guerra, Rui; Barreira, Luísa A.; Perales, José A.; Varela, João C.S.. 2016. "Effect of light quality supplied by light emitting diodes (LEDs) on growth and biochemical profiles of Nannochloropsis oculata and Tetraselmis chuii". Algal Research, 16: 387-398. https://doi.org/10.1016/j.algal.2016.03.034
Gangadhar, Katkam N.; Pereira, Hugo; Diogo, Hermínio P.; Borges dos Santos, Rui M.; Prabhavathi Devi, B. L. A.; Prasad, R. B. N.; Custódio, Luísa; et al. 2015. "Assessment and comparison of the properties of biodiesel synthesized from three different types of wet microalgal biomass". Journal of Applied Phycology, 28 (3): 1571-1578. https://doi.org/10.1007/s10811-015-0683-5
Roggatz, Christina C.; González-Wangüemert, Mercedes; Pereira, Hugo; Rodrigues, Maria João; da Silva, Manuela Moreira; Barreira, Luísa; Varela, João; Custódio, Luísa. 2015. "First report of the nutritional profile and antioxidant potential ofHolothuria arguinensis, a new resource for aquaculture in Europe". Natural Product Research, 30 (18): 2034-2040. https://doi.org/10.1080/14786419.2015.1107555
Rodrigues, Maria João; Soszynski, Ambre; Martins, Alice; Rauter, Amélia P.; Neng, Nuno R.; Nogueira, José M.F.; Varela, João; Barreira, Luísa; Custódio, Luísa. 2015. "Unravelling the antioxidant potential and the phenolic composition of different anatomical organs of the marine halophyte Limonium algarvense". Industrial Crops and Products, 77: 315-322. https://doi.org/10.1016/j.indcrop.2015.08.061
Custódio, Luísa; Laukaityte, Simona; Engelen, Aschwin H.; Rodrigues, Maria João; Pereira, Hugo; Vizetto-Duarte, Catarina; Barreira, Luísa; et al. 2015. "A comparative evaluation of biological activities and bioactive compounds of the seagrasses Zostera marina and Zostera noltei from southern Portugal". Natural Product Research, 30 (6): 724-728. https://doi.org/10.1080/14786419.2015.1040791
Varela, João C.; Pereira, Hugo; Vila, Marta; León, Rosa. 2015. "Erratum to: Production of carotenoids by microalgae: achievements and challenges". Photosynthesis Research, 127 (2): 285-286. https://doi.org/10.1007/s11120-015-0183-0
Varela, João C.; Pereira, Hugo; Vila, Marta; León, Rosa. 2015. "Production of carotenoids by microalgae: achievements and challenges". Photosynthesis Research, 125 (3): 423-436. https://doi.org/10.1007/s11120-015-0149-2
Vizetto-Duarte, Catarina; Pereira, Hugo; Bruno de Sousa, Carolina; Pilar Rauter, Amélia; Albericio, Fernando; Custódio, Luísa; Barreira, Luísa; Varela, João. 2015. "Fatty acid profile of different species of algae of the Cystoseira genus: a nutraceutical perspective". Natural Product Research, 29 (13): 1264-1270. https://doi.org/10.1080/14786419.2014.992343
Grosso, Carla; Cardoso, Ana Lúcia; Lemos, Américo; Varela, João; Rodrigues, Maria João; Custódio, Luísa; Barreira, Luísa; Pinho e Melo, Teresa M.V.D.. 2015. "Novel approach to bis(indolyl)methanes: De novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties". European Journal of Medicinal Chemistry, 93: 9-15. https://doi.org/10.1016/j.ejmech.2015.01.050
Custódio, Luísa; Soares, Fernando; Pereira, Hugo; Rodrigues, Maria João; Barreira, Luísa; Rauter, Amélia Pilar; Alberício, Fernando; Varela, João. 2014. "Botryococcus braunii and Nannochloropsis oculata extracts inhibit cholinesterases and protect human dopaminergic SH-SY5Y cells from H2O2-induced cytotoxicity". Journal of Applied Phycology, 27 (2): 839-848. https://doi.org/10.1007/s10811-014-0369-4
Schulze, Peter S.C.; Barreira, Luísa A.; Pereira, Hugo G.C.; Perales, José A.; Varela, João C.S.. 2014. "Light emitting diodes (LEDs) applied to microalgal production". Trends in Biotechnology, 32 (8): 422-430. https://doi.org/10.1016/j.tibtech.2014.06.001
Martins, Alice; Mignon, Rukmini; Bastos, Marina; Batista, Daniela; Neng, Nuno R.; Nogueira, José M. F.; Vizetto-Duarte, Catarina; et al. 2014. "In vitro Antitumoral Activity of Compounds Isolated from Artemisia gorgonum Webb". Phytotherapy Research, 28 (9): 1329-1334. https://doi.org/10.1002/ptr.5133
Rodrigues, Maria; Gangadhar, Katkam; Vizetto-Duarte, Catarina; Wubshet, Sileshi; Nyberg, Nils; Barreira, Luísa; Varela, João; Custódio, Luísa. 2014. "Maritime Halophyte Species from Southern Portugal as Sources of Bioactive Molecules". Marine Drugs, 12 (4): 2228-2244. https://doi.org/10.3390/md12042228
Sutherland, Alastair D; Varela, Joao C. 2014. "Comparison of various microbial inocula for the efficient anaerobic digestion of Laminaria hyperborea". BMC Biotechnology, 14 (1). https://doi.org/10.1186/1472-6750-14-7
Varela, João. " Os oceanos e a biotecnologia marinha: um novo desafio para Portugal. ". Boletim de Biotecnologia, 5 (2014): 8-10. http://www.forumoceano.pt/files/6_Comunicacao/61_artigos/Boletim_SPBT_julh2014.pdf?d=37fr
Custódio, Luísa; Soares, Fernando; Pereira, Hugo; Barreira, Luísa; Vizetto-Duarte, Catarina; Rodrigues, Maria João; Rauter, Amélia Pilar; Alberício, Fernando; Varela, João. 2013. "Fatty acid composition and biological activities of Isochrysis galbana T-ISO, Tetraselmis sp. and Scenedesmus sp.: possible application in the pharmaceutical and functional food industries". Journal of Applied Phycology, 26 (1): 151-161. https://doi.org/10.1007/s10811-013-0098-0
Martins, Dulce; Custódio, Luísa; Barreira, Luísa; Pereira, Hugo; Ben-Hamadou, Radhouan; Varela, João; Abu-Salah, Khalid. 2013. "Alternative Sources of n-3 Long-Chain Polyunsaturated Fatty Acids in Marine Microalgae". Marine Drugs, 11 (7): 2259-2281. https://doi.org/10.3390/md11072259
Pereira, Hugo; Barreira, Luísa; Custódio, Luísa; Alrokayan, Salman; Mouffouk, Fouzi; Varela, João; Abu-Salah, Khalid; Ben-Hamadou, Radhouan. 2013. "Isolation and Fatty Acid Profile of Selected Microalgae Strains from the Red Sea for Biofuel Production". Energies, 6 (6): 2773-2783. https://doi.org/10.3390/en6062773
Hernández-Prieto, Miguel A.; Schön, Verena; Georg, Jens; Barreira, Luísa; Varela, João; Hess, Wolfgang R.; Futschik, Matthias E.. 2012. "Iron Deprivation in Synechocystis: Inference of Pathways, Non-coding RNAs, and Regulatory Elements from Comprehensive Expression Profiling". G3: Genes|Genomes|Genetics, 2 (12): 1475-1495. https://doi.org/10.1534/g3.112.003863
Pereira, Hugo; Barreira, Luísa; Figueiredo, Filipe; Custódio, Luísa; Vizetto-Duarte, Catarina; Polo, Cristina; Rešek, Eva; Engelen, Aschwin; Varela, João. 2012. "Polyunsaturated Fatty Acids of Marine Macroalgae: Potential for Nutritional and Pharmaceutical Applications". Marine Drugs, 10 (12): 1920-1935. https://doi.org/10.3390/md10091920
Custódio, Luísa; Ferreira, Ana Catarina; Pereira, Hugo; Silvestre, Laura; Vizetto-Duarte, Catarina; Barreira, Luísa; Rauter, Amélia Pilar; Alberício, Fernando; Varela, João. 2012. "The marine halophytes Carpobrotus edulis L. and Arthrocnemum macrostachyum L. are potential sources of nutritionally important PUFAs and metabolites with antioxidant, metal chelating and anticholinesterase inhibitory activities". Botanica Marina, 55 (3). https://doi.org/10.1515/bot-2012-0098
Custódio, Luísa; Justo, Tiago; Silvestre, Laura; Barradas, Ana; Duarte, Catarina Vizetto; Pereira, Hugo; Barreira, Luísa; et al. 2012. "Microalgae of different phyla display antioxidant, metal chelating and acetylcholinesterase inhibitory activities". Food Chemistry, 131 (1): 134-140. https://doi.org/10.1016/j.foodchem.2011.08.047
Pereira, Hugo; Barreira, Luísa; Mozes, André; Florindo, Cláudia; Polo, Cristina; Duarte, Catarina V; Custódio, Luísa; Varela, João. 2011. "Microplate-based high throughput screening procedure for the isolation of lipid-rich marine microalgae". Biotechnology for Biofuels, 4 (1). https://doi.org/10.1186/1754-6834-4-61
Ramos, Ana A.; Polle, Jurgen; Tran, Duc; Cushman, John C.; Jin, Eon-Seon; Varela, Joao C.. 2011. "The unicellular green alga Dunaliella salina Teod. as a model for abiotic stress tolerance: genetic advances and future perspectives". ALGAE, 26 (1): 3-20. https://doi.org/10.4490/algae.2011.26.1.003
Ramos, Ana A.; Marques, Ana R.; Rodrigues, Marta; Henriques, Nuno; Baumgartner, Alexandra; Castilho, Rita; Brenig, Bertram; Varela, João C.. 2009. "Molecular and functional characterization of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Dunaliella salina". Journal of Plant Physiology, 166 (9): 968-977. https://doi.org/10.1016/j.jplph.2008.11.008
Coesel, Sacha; Oborník, Miroslav; Varela, Joao; Falciatore, Angela; Bowler, Chris. 2008. "Evolutionary Origins and Functions of the Carotenoid Biosynthetic Pathway in Marine Diatoms". PLoS ONE, 3 (8). https://doi.org/10.1371/journal.pone.0002896
Mendoza, Héctor; de la Jara, Adelina; Freijanes, Karen; Carmona, Laura; Ramos, Ana Alexandra; de Sousa Duarte, Vanessa; Serafim Varela, João Carlos. 2008. "Characterization of Dunaliella salina strains by flow cytometry: a new approach to select carotenoid hyperproducing strains". Electronic Journal of Biotechnology, 11 (4): 0-0. https://doi.org/10.2225/vol11-issue4-fulltext-2
Coesel, Sacha Nicole; Baumgartner, Alexandra Cordeiro; Teles, Licia Marlene; Ramos, Ana Alexandra; Henriques, Nuno Miguel; Cancela, Leonor; Varela, João Carlos Serafim. 2008. "Nutrient Limitation is the Main Regulatory Factor for Carotenoid Accumulation and for Psy and Pds Steady State Transcript Levels in Dunaliella salina (Chlorophyta) Exposed to High Light and Salt Stress". Marine Biotechnology, 10 (5): 602-611. https://doi.org/10.1007/s10126-008-9100-2
Ramos, Ana Alexandra Pedrosa; Varela, João Carlos Serafim. 2008. "Biochemistry and molecular biology in Portugal: An overview of past and current contributions". IUBMB Life, 60 (5): 265-269. https://doi.org/10.1002/iub.65
Varela, João. " Dunaliella: uma fonte natural de ß-caroteno com potencialidades de aproveitamento biotecnológico.". Boletim de Biotecnologia, 1998: 12-18.
Varela, J. C. S.; Mager, W. H.. 1996. "Response of Saccharomyces cerevisiae to changes in external osmolarity". Microbiology, 142 (4): 721-731. https://doi.org/10.1099/00221287-142-4-721
Varela, J C; Praekelt, U M; Meacock, P A; Planta, R J; Mager, W H. 1995. "The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A.". Molecular and Cellular Biology, 15 (11): 6232-6245. https://doi.org/10.1128/mcb.15.11.6232
Mager, Willem H.; Varela, João C. S.. 1993. "Osmostress response of the yeastSaccharomyces". Molecular Microbiology, 10 (2): 253-258. https://doi.org/10.1111/j.1365-2958.1993.tb01951.x
Varela, Joäo C. S.; Beekvelt, Catelijne; Planta, Rudi J.; Mager, Willem H.. 1992. "Osmostress-induced changes in yeast gene expression". Molecular Microbiology, 6 (15): 2183-2190. https://doi.org/10.1111/j.1365-2958.1992.tb01392.x
