Sofia M. Calado
Investigador doutorado
Subsistema
Investigadores
Regime
Exclusividade
Vínculo
CT em Funções Públicas a termo resolutivo certo
Education: PhD in Biomedical Sciences from the University of the Algarve, Portugal, graduated with "High Distinction and Honor". Current position: Postdoctoral Researcher at the Stem Cell lab, ABC-RI. Research line: Development of in vitro models of congenital heart diseases, using iPS cells derived from human patient samples. Sofia Calado was recently awarded with a Stimulus of Scientific Employment, Individual Support - 3rd Edition Contract to start in 2021. Participation in Research Projects: Total = 10 (6 National Projects in Portugal, 1 European Project and 3 National Project in Spain). Publications: Including original papers = 25. H-index = 11 (Google Scholar). Citations = 611 (Google Scholar). Communications in national and international meetings: Total of 21, including 2 oral communications and 3 oral invited communication. Supervision of students: Supervision of 3 theses (2 BSc and 1 MSc); Co-supervision of 5 theses (4 BSc; 1 MSc thesis and 1 PhD thesis). Teaching experience: Teaching assistant in 9 different courses for undergraduate and master students. Prizes received: Merit scholarship from the University of the Algarve; PhD scholarship from Portuguese Foundation for Science and Technology; and two travel scholarships to attend international conferences. Other merits: Collaborator in four outreach events; Chair in the ESGCT Spring School, 2017 Edition; Member of the editorial board of The Journal of Human Physiology. Experience in national and international R&D centers: CBMR = 6 years, CEDOC = 5 months, CABIMER = 2 years and 10 months, Harvard Medical School: 1 month. Active Memberships: 2 (SPD; ISCT). Participation in International networks: 1 (EYE-RISK Consortium).
Atividades
Atividades
2022/02 - 2023/05. Organização de evento. FENS Regional Meeting 2023 (2022). Algarve Biomedical Center Research Institute.
2022/03/10. Apresentação oral de trabalho. Impact and causative role of the VE-PTP gene variant in the pathophysiology of Left Ventricular Noncompaction Cardiomyopathy. 12th International Meeting of the SPCE-TC. Portuguese Society for Stem Cells and Cell Therapies (Braga, Portugal).
2021/10/01 - 2022/01/31. Curso / Disciplina lecionado. Gene and Cell Therapy - Practical Classes. Licenciatura em Ciências Biomédicas (Licenciatura). Universidade do Algarve Departamento de Ciências Biomédicas e Medicina.
2022/01/10 - 2022/01/31. Curso / Disciplina lecionado. Oncolabs 1. Mestrado em Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado). Universidade do Algarve Departamento de Ciências Biomédicas e Medicina.
2021/12/13 - 2021/12/14. Comissão de avaliação. Avaliador nas Jornadas do Doutorandos em Ciências Biomédicas. Universidade do Algarve Departamento de Ciências Biomédicas e Medicina.
2021/12/02. Apresentação oral de trabalho. Compacting Left Ventricular Noncompaction Cardiomyopathy in cellular models to study the pathological mechanisms
. International Conference on Human Genetics and Genomics. Yazd University (Irão).
. International Conference on Human Genetics and Genomics. Yazd University (Irão).
2021/11 - Presente. Orientação. Impact and causative role of the VE-PTP gene variant in the pathophysiology of Left Ventricular Noncompaction Cardiomyopathy..Ciências Biomédicas (Doutoramento). Coorientador.
2021/10/13 - 2021/10/13. Organização de evento. Dia das Células Estaminais (2021). Algarve Biomedical Center Research Institute.
2021/10/08. Apresentação oral de trabalho. From the patients to the bench looking for answers. IV Jornadas do Algarve Biomedical Center. Algarve Biomedical Center (Moura, Portugal).
2021/09 - Presente. Orientação. Creating mini-hearts in vitro Modeling left ventricular noncompaction cardiomyopathy in cardioids.Ciências Biomédicas (Mestrado). Orientador.
2021/05 - 2021/07. Orientação. Avaliação das alterações vasculares em modelos de células estaminais pluripotentes
induzidas de doentes com miocardiopatia não compactada.Ciências Biomédicas (Licenciatura/Bacharelato). Orientador.
induzidas de doentes com miocardiopatia não compactada.Ciências Biomédicas (Licenciatura/Bacharelato). Orientador.
2021/05 - 2021/07. Orientação. Utilização de células estaminais pluripotentes induzidas como modelo celular de miocardiopatia não compactada.Ciências Biomédicas (Licenciatura/Bacharelato). Orientador.
2021/07/27. Júri de grau académico. Expressão da proteína Mgp nas estruturas oculares do peixe zebra: contribuição para estudos sobre a síndrome de Keutel.. Carolina Deus Rodrigues (Outro). Universidade do Algarve.
2021/07/07. Júri de grau académico. Role of interferon-induced PKR as predictive biomarker and anti-cancer stem cells properties of interferon. Arguente. María Belén García Ortega (Doutoramento). Universidad de Granada.
2021/06/01. Júri de grau académico. Terapias Avanzadas en Enfermedades Degenerativas de la Retina. Arguente. Ana Belén Garcá Delgado (Doutoramento). Universidad de Sevilla.
2021/05/24 - 2021/05/28. Organização de evento. Organizing Committee of "The CRISPR Revolution: a workshop on gene editing, from cells to animal models" (2021). Universidade do Algarve.
2021/01/01 - 2021/02/01. Curso / Disciplina lecionado. Oncolabs 1. Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado integrado). Universidade do Algarve.
2020/10 - 2021/01. Curso / Disciplina lecionado. Gene Therapy Classes - Practical Classes. Ciências Biomédicas (Licenciatura). Universidade do Algarve.
2020/12/11. Júri de grau académico. Biodistribution Analysis of Striatal and Cerebellar Administration of Modified Adeno-Associated Viral Vectors in Normal Mice. Arguente. Inês Torquato Afonso (Mestrado). Universidade do Algarve - Campus de Gambelas.
2020/10 - Presente. Organização de evento. Organisation Committee of the LabClub Seminar - 2020/2021 Season (2020). Universidade do Algarve Centro de Investigação em Biomedicina.
2020/09/20. Júri de grau académico. Avaliação da toxicidade sistémica e local da terapia génica mediada por vetores virais. Inês de Oliveira Valente (Outro). Universidade do Algarve - Campus de Gambelas.
2020/07 - Presente. Membro de associação. International Society of Cell and Gene Therapy. Member.
2020/07/29. Júri de grau académico. Animal models in the study of cancer therapeutics-related cardiac dysfunction . Arguente. BRUNA ISABEL MACHADO DE CAMPOS (Outro). Universidade do Algarve - Campus de Gambelas.
2020/03/23 - Presente. Participação em evento. Volunteer for COVID-19 Diagnostic Tests at CBMR in collaboration with ABC and ARS-Algarve. Outro. CBMR VOLUNTARY EXCHANGE FOR COVID-19 DIAGNOSTIC TESTS. Universidade do Algarve - Campus de Gambelas.
2020/02/20 - 2020/02/20. Participação em evento. Collaborator in the UAlg Open Day for high school students. Outro. UAlg Open Day. Universidade do Algarve - Campus de Gambelas.
2012/09/20 - 2019/11/30. Curso / Disciplina lecionado. Teaching Assistant of the “Cellular Biology” course (12 hours).. Ciências Biomédicas (Licenciatura). Universidade do Algarve.
2019/09 - Presente. Orientação. Modelling LVNC using patient-derived iPSC..Ciências Biomédicas (Mestrado). Orientador.
2019/08 - Presente. Arbitragem científica em revista. Journal of Human Physiology (2661-3859). Bilingual Publishing Co..
2014/05/19 - 2019/05/19. Curso / Disciplina lecionado. Invited talk in the Gene and Cell Therapy undergraduate course. Topic: “Episomal vectors for efficient gene transfer to the retina”. . Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2019/03/25 - 2019/04/09. Curso / Disciplina lecionado. Human Genetics. Farmácia (Licenciatura). Universidade do Algarve.
2019/03/15 - 2019/03/20. Curso / Disciplina lecionado. Molecular Biology. Universidade do Algarve.
2017 - 2017. Participação em evento. Co-chair in the Spring School of the European Society for Gene and Cell Therapy. Conferência. Spring School of the European Society for Gene and Cell Therapy.
2017/07. Apresentação oral de trabalho. Patient-specific iPSC-derived RPE for modeling AMD. Young Researcher Vision Camp .
2017/04 - 2017/06. Participação em evento. Participation in the Online course (38 hours) on Good Laboratory Practice (GLP). Fundación Pública Andaluza Progreso y Salud; Iniciativa Andaluza de Terapias Avanzadas.
2017/04/24 - 2017/04/24. Curso / Disciplina lecionado. Invited talk in the Research Methods in Biomedicine Master’s course. Topic: “Non-viral gene therapy for retinal dystrophies using self-replicating systems”. Ciências Biomédicas (Mestrado). Universidade dos Açores.
2016 - 2016. Entrevista / Programa (rádio / tv). Maratona da Saúde, 2016 Edition. Diabetes.
2016 - Presente. Membro de associação. Portuguese Society of Diabetes. Member.
2016/07. Apresentação oral de trabalho. PEDF ameliorates Diabetic Retinopathy. 1st Symposium on Chronic Diseases. Center of Chronic Diseases (CEDOC) (Lisboa, Portugal).
2015/09/26 - 2015/11/30. Curso / Disciplina lecionado. Teaching Assistant of the “Tissues, Cells and Molecules”. Medicina (Mestrado integrado). Universidade Nova de Lisboa.
2015/11/11 - 2015/11/11. Curso / Disciplina lecionado. Invited talk in the Human Genetics undergraduate course. Topic: “Gene Therapy for Retinal Pathologies”. Ciclo Básico de Medicina. Universidade dos Açores.
2014/09 - 2015/09. Orientação. Characterization of pro- and anti-angiogenic factors in models of Diabetic Retinopathy.Ciências Biomédicas (Mestrado). Coorientador.
2015/02 - 2015/04. Tutoria. Evaluation of VEGFR1 expression levels in in vitro models of diabetic retinopathy. Joana Canadas.
2014/09/20 - 2014/11/30. Curso / Disciplina lecionado. Teaching Assistant of the “Gene and Cell Therapy” course. Ciências Biomédicas (Licenciatura). Universidade do Algarve.
2014/04 - 2014/07. Orientação. Importance of the imbalance between pro- and anti-angiogenic factors for the development and progression of diabetic retinopathy.Ciências Biomédicas. Coorientador.
2014/02/01 - 2014/03/31. Curso / Disciplina lecionado. Teaching Assistant of the “Animal Cell Biology” course . Ciências Biomédicas (Licenciatura). Universidade do Algarve.
2014/02/23 - 2014/02/23. Curso / Disciplina lecionado. Invited talk in the Tissue Culture undergraduate course. Topic: “Cell culture as an in vitro model of diabetic retinopathy”.. Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2013 - 2013. Participação em evento. Collaborator in the organization of the Brain Awareness Week. Brain Awareness Week. Universidade do Algarve - Campus de Gambelas.
2013/10. Apresentação oral de trabalho. Hyperglycemia and oxygen tension control the expression of the glucose transporter GLUT-1 in models of Diabetic Retinopathy. European Society for Gene and Cell Therapy. Sociedad Española de Terapia Génica y Celular (Madrid, Espanha).
2013/04 - 2013/07. Orientação. Evaluation of GLUT-1 expression in models of diabetic retinopathy.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador.
2013/05/16 - 2013/05/16. Curso / Disciplina lecionado. Invited talk in the Gene and Cell Therapy undergraduate course. Topic: . “S/MARs-based plasmids for long-term gene delivery”. Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2013/03 - 2013/03. Participação em evento. Participation in the Introductory course on “Light Microscopy”. Universidade do Algarve - Campus de Gambelas.
2013/03 - 2013/03. Participação em evento. Participation in the workshop on “Non statistics with R” (4 hours) . Universidade do Algarve - Campus de Gambelas.
2013/03/03 - 2013/03/03. Curso / Disciplina lecionado. Invited talk in the Tissue Culture undergraduate course. Topic: “The importance of cell cultures for gene therapy”. . Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2012 - 2012. Participação em evento. Collaborator in the organization of the Brain Awareness Week. Brain Awareness Week. Universidade do Algarve - Campus de Gambelas.
2012 - 2012. Participação em evento. Collaborator in the organization of the “Dia aberto CBME/DCBM – Cientista e Médico”. Dia aberto CBME/DCBM – Cientista e Médico. Universidade do Algarve - Campus de Gambelas.
2012/09/23 - 2012/11/30. Curso / Disciplina lecionado. Teaching Assistant of the “Cellular Biology” course. Ciências Biomédicas (Licenciatura). Universidade do Algarve.
2012/05 - 2012/07. Orientação. Histological evaluation of retinal thickness of Ins2Akita mice.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador.
2012/06 - 2012/06. Participação em evento. Creditation of the Online course on “Science of Laboratory Animals” (20 hours) according with FELASA, Category B, conferred by SPCAL. Sociedade Portuguesa de Ciências em Animais de Laboratório.
2012/05 - 2012/06. Participação em evento. Participation in the workshop on “Development of scientific skills” (12 hours). Universidade do Algarve - Campus de Gambelas.
2012/05/22 - 2012/05/22. Curso / Disciplina lecionado. Invited talk in the Gene and Cell Therapy undergraduate course. Topic: “S/MARs, the solution for long-term expression”. Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2012/04 - 2012/04. Participação em evento. Participation in the advanced course on “Animal models for Human Diseases”. Universidade de Coimbra.
2012/04/01 - 2012/04/04. Curso / Disciplina lecionado. “Tissue Regeneration and Reconstruction” course. Ciências Biomédicas (Mestrado integrado). Universidade do Algarve.
2012/02 - 2012/02. Participação em evento. Participation in the advanced course on “Brain and ocular diseases: How to overcome the barriers” . Universidade de Coimbra.
2012/02/14 - 2012/02/14. Curso / Disciplina lecionado. Invited talk in the Tissue Culture undergraduate course. Topic: “Evaluation of pEPi-1 and pEPito expression systems for gene transfer to retinal cells”. Ciências Biomédicas (Licenciatura). Universidade do Algarve - Campus de Gambelas.
2011/05 - 2011/07. Orientação. Apoptosis and microglial reactivity in the retina of Ins2Akita mice.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador.
2011/07 - 2011/07. Participação em evento. Creditation of the practical course on “Use of rodents, fish and amphibian in scientific investigation” (20 hours) according with FELASA, Category B, conferred by SPCAL. Use of rodents, fish and amphibian in scientific investigation. Sociedade Portuguesa de Ciências em Animais de Laboratório.
2011/07 - 2011/07. Participação em evento. Participation in the advanced course on “Human genetics: from basic science to clinics and genetic counseling” . Human genetics: from basic science to clinics and genetic counseling. Universidade do Algarve - Campus de Gambelas.
Projetos
Projetos
2018/01/01 - 2019/02/28. Pre-clinical study to evaluate hybrid drugs to modulate sirtuin-1 and VEGF as a therapeutic strategy for age-related macular degeneration and diabetic retinopathy. Outra. Centro Andaluz de Biología Molecular y Medicina Regenerativa.
2021 - 2027. Identification and functional analysis of genetic variants in left ventricular noncompaction cardiomyopathy, Concurso de Estímulo ao Emprego Científico - 3ª Edição. Investigador responsável. Universidade do Algarve.
2023/01 - 2025/01. Non-invasive approach to limit congenital heart disease in mammalian embryos in utero, Translational Research Prize “José Mariano Gago by ABC”. Investigador. Algarve Biomedical Center Research Institute.
2023/01 - 2025/01. Development of a pipeline into unravelling the molecular and cellular basis of rare neurologic diseases, First Translational Medicine Prize "João Larguito by ABC". Co-Investigador Responsável (Co-IR). Algarve Biomedical Center Research Institute.
2022/02/01 - 2023/01/31. Functional analysis of new genetic variants in left ventricular noncompaction cardiomyopathy, PROJETOS DE INVESTIGAÇÃO EXPLORATÓRIOS NOS DOMÍNIOS CIENTÍFICOS DO ABC-RI. Investigador responsável. Algarve Biomedical Center Research Institute.
2022/01 - Presente. Identification of S-sulfhydration targets in Down Syndrome: the role of gasotransmitter hydrogen sulfide (H2S) signaling in neurodevelopment. Investigador. Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarve (AD-ABC); Algarve Biomedical Center Research Institute.
2020/05/01 - 2020/10/30. Development of a new assay do detect SARS-CoV-2 directly from clinical samples, RESEARCH4COVID 19. Outra. Universidade do Algarve Centro de Investigação em Biomedicina.
2019/03/01 - Presente. VITAL: Variant sequences Identification genome wide and Their Assignment as true causative mutations for LVNC. Investigador.
2016/09/19 - 2019/02/28. Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways. Investigador. Centro Andaluz de Biología Molecular y Medicina Regenerativa.
2017/07/01 - 2019/02/28. Application of genomics and epigenomics in the generation of stem cells derived from patients suffering from retinitis pigmentosa due to EYS mutations. Outra. Centro Andaluz de Biología Molecular y Medicina Regenerativa.
2019/01/01 - 2019/02/28. Pre-clinical trial of ex vivo gene editing therapy for retinitis pigmentosa. Outra. Centro Andaluz de Biología Molecular y Medicina Regenerativa.
2016/04/01 - 2016/09/16. SynDia: the role of synucleins in diabetic retinopathy. Investigador. iNOVA4Health.
2014/01 - 2015/03. RASRET - Role of the renin-angiotensin system in retinal diseases and its therapeutic potential.
Produções
Calado, Sofia M.; Bento, Dina; Justino, David; Mendes-Silva, Leonardo; Marques, Nuno; Bragança, José. 2021. "Generation of a human induced pluripotent stem cell line (UALGi001-A) from a patient with Left-Ventricular Noncompaction Cardiomyopathy". Stem Cell Research. https://doi.org/10.1016/j.scr.2021.102302
Calado, Sofia M.; Bento, Dina; Marques, Nuno; Bragança, José. 2021. "Generation and cardiac differentiation of a human induced pluripotent stem cell line UALGi002-A from a female patient with Left-Ventricular Noncompaction Cardiomyopathy". Stem Cell Research, 55. https://doi.org/10.1016/j.scr.2021.102462
Fernandes, Mónica T; Calado, Sofia M; Mendes-Silva, Leonardo; Bragança, José. 2020. "CITED2 and the modulation of the hypoxic response in cancer". World Journal of Clinical Oncology, 11 (5): 260-274. https://doi.org/10.5306/wjco.v11.i5.260
Ajana, Soufiane; Cougnard-Grégoire, Audrey; Colijn, Johanna M.; Merle, Bénédicte M.J.; Verzijden, Timo; de Jong, Paulus T.V. M.; Hofman, Albert; et al. 2020. "Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning". Ophthalmology. https://doi.org/10.1016/j.ophtha.2020.08.031
Acar, Ilhan E.; Lores-Motta, Laura; Colijn, Johanna M.; Meester-Smoor, Magda A.; Verzijden, Timo; Cougnard-Gregoire, Audrey; Ajana, Soufiane; et al. 2020. "Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration". Ophthalmology. https://doi.org/10.1016/j.ophtha.2020.06.020
Bitoque, Diogo B.; Morais, Joana; Oliveira, Ana V.; Sequeira, Raquel L.; Calado, Sofia M.; Fortunato, Tiago M.; Simão, Sonia; Rosa da Costa, Ana M.; Silva, Gabriela A.. 2020. "Human-derived NLS enhance the gene transfer efficiency of chitosan". Bioscience Reports. https://doi.org/10.1042/bsr20201026
Garcia-Delgado, Ana B.; Calado, Sofia M.; Valdes-Sanchez, Lourdes M.; Montero-Sanchez, Adoracion; Ponte-Zuñiga, Beatriz; de la Cerda, Berta; Bhattacharya, Shom Shanker; Diaz-Corrales, Francisco J.. 2019. "Generation of a human iPS cell line (CABi003-A) from a patient with age-related macular degeneration carrying the CFH Y402H polymorphism". Stem Cell Research, 38. https://doi.org/10.1016/j.scr.2019.101473
de la Cerda B; Díez-Lloret A; Ponte B; Vallés-Saiz L; Calado SM; Rodríguez-Bocanegra E; Garcia-Delgado AB; et al. 2019. "Generation and characterization of the human iPSC line CABi001-A from a patient with retinitis pigmentosa caused by a novel mutation in PRPF31 gene.". Stem cell research. https://doi.org/10.1016/j.scr.2019.101426
Sofia M. Calado. 2019. "CITED Proteins in the Heart of Pluripotent Cells and in Heart’s Full Potential". Regenerative Medicine Frontiers. https://doi.org/10.20900/rmf20190005
Kersten, Eveline; Dammeier, Sascha; Ajana, Soufiane; Groenewoud, Joannes M. M.; Codrea, Marius; Klose, Franziska; Lechanteur, Yara T.; et al. 2019. "Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway". PLOS ONE, 14 (6). https://doi.org/10.1371/journal.pone.0218457
Calado, Sofia M.; Valdés-Sánchez, Lourdes; de la Cerda, Berta; Aramburu, Ana; García-Delgado, Ana Belén; Massalini, Simone; Montero-Sánchez, Adoración; et al. 2019. "Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins". Molecular Medicine, 26 (1). https://doi.org/10.1186/s10020-019-0124-z
García Delgado, Ana B.; de la Cerda, Berta; Alba Amador, Julia; Valdés Sánchez, Maria Lourdes; Fernández-Muñoz, Beatriz; Relimpio López, Isabel; Rodríguez de la Rúa, Enrique; et al. 2019. "Subretinal Transplant of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium on Nanostructured Fibrin-Agarose". Tissue Engineering Part A, 25 (9-10): 799-808. https://doi.org/10.1089/ten.tea.2019.0007
Calado SM; Garcia-Delgado AB; De la Cerda B; Ponte-Zuñiga B; Bhattacharya SS; Díaz-Corrales FJ. 2018. "Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation.". Stem cell research. https://doi.org/10.1016/j.scr.2018.11.002
Colijn JM; den Hollander AI; Demirkan A; Cougnard-Grégoire A; Verzijden T; Kersten E; Meester-Smoor MA; et al. 2018. "Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia.". Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.09.045
Carvalho FR; Calado SM; Silva GA; Diogo GS; Moreira da Silva J; Reis RL; Cancela ML; Gavaia PJ. 2018. "Altered bone microarchitecture in a type 1 diabetes mouse model Ins2Akita.". Journal of cellular physiology. https://doi.org/10.1002/jcp.27617
Merle BMJ; Colijn JM; Cougnard-Grégoire A; de Koning-Backus APM; Delyfer MN; Kiefte-de Jong JC; Meester-Smoor M; et al. 2018. "Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration: The EYE-RISK Consortium.". Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.08.006
Garcia-Delgado AB; Valdés-Sánchez L; Calado SM; Diaz-Corrales FJ; Bhattacharya SS. 2018. "Cover.". CNS neuroscience & therapeutics. https://doi.org/10.1111/cns.12870
Garcia-Delgado AB; Valdés-Sánchez L; Calado SM; Diaz-Corrales FJ; Bhattacharya SS. 2018. "Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression.". CNS neuroscience & therapeutics. https://doi.org/10.1111/cns.12805
Brown, Connor; Green, Brian; Thompson, Richard; den Hollander, Anneke; EYE-RISK Consortium; Lengyel, Imre. 2018. "Metabolomics and Age-Related Macular Degeneration". Metabolites, 9 (1). https://doi.org/10.3390/metabo9010004
Diaz-Corrales, Francisco J.; Morales-Sanchéz, J.C.; Valdés-Sánchez, Lourdes; Garcia-Delgado, Ana B.; Montero-Sanchez, Adoracion; Sofia M. Calado; de la Cerda, Berta; Bhattacharya, Shom S.. 2018. The hybrid drug JC21 delays retinal degeneration in a mouse model of age-related macular degeneration. Em International Symposium on retinal Degeneration.
Sofia M. Calado. 2017. "Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future.". Ophthalmology. https://doi.org/10.1016/j.ophtha.2017.05.035
Garcia-Delgado, Ana B.; Valdés-Sánchez, Lourdes; Sofia M. Calado; Diaz-Corrales, Francisco J.; Bhattacharya, Shom S.. 2017. Rasagiline decreased photoreceptor degeneration through Bcl2 pathway. Em Alzheimer's & Parkinson's Diseases Congress.
Diaz-Corrales, Francisco J.; Morales-Sanchéz, J.C.; Valdés-Sánchez, Lourdes; Lucas-Rodriguez, R.; Garcia-Delgado, Ana B.; Penãlver, P.; Sofia M. Calado; et al. 2017. The hybrid drug JC21 delays retinal degeneration in a mouse model of RPE atrophy with pseudo-drusen. A new neuroprotective molecule for Age-related Macular Degeneration treatment. Em Alzheimer's & Parkinson's Diseases Congress.
Calado, S.M.; Diaz-Corrales, F.; Silva, G.A.; Calado, Sofia M.; Diaz-Corrales, Francisco; Silva, Gabriela A.. 2016. "PEPito-driven PEDF Expression Ameliorates Diabetic Retinopathy Hallmarks". Human Gene Therapy Methods, 27 (2): 79-86. https://doi.org/10.1089/hgtb.2015.169
Sofia M. Calado. 2016. "GLUT1 activity contributes to the impairment of PEDF secretion by the RPE.". Molecular vision. http://europepmc.org/abstract/med/27440994
Sofia M. Calado; Diaz-Corrales, Francisco J.; Gabriela A. Silva. 2016. "Terapia Génica com PEDF reduz principais marcadores de Retinopatia Diabética". Trabalho apresentado em 12º Congresso Português de Diabetes, Loulé, Portugal, 11 (1).
Sónia Simão; Bitoque, Diogo; Sofia M. Calado; Gabriela A. Silva. 2016. "Increased expression of (pro)renin and (pro)renin receptor correlates with the progression of diabetic retinopathy". Trabalho apresentado em EURETINA, Copenhaga, Dinamarca, 236 (Supp1), 1-67.
Sofia M. Calado; Simão, Sónia; B Bitoque, Diogo; M Calado, Sofia; A Silva, Gabriela. 2016. "Oxidative stress modulates the expression of VEGF isoforms in models of diabetic retinopathy". New Frontiers in Ophthalmology, 2 (2). https://doi.org/10.15761/NFO.1000119
Sofia M. Calado. 2016. "Multifactorial approach to non-viral gene therapy: development of an efficient system for the retina". Doutoramento. https://sapientia.ualg.pt/handle/10400.1/8409
Sofia M. Calado; Diaz-Corrales, Francisco J.; Gabriela A. Silva. 2016. Terapia Génica com PEDF reduz principais marcadores de retinopatia diabética. Em 12º Congresso Português de Diabetes.
Sónia Simão; Bitoque, Diogo; Sofia M. Calado; Gabriela A. Silva. 2016. Increased expression of (pro)renin and (pro)renin receptor correlates with the progression of diabetic retinopathy. Em EURETINA.
Joana Morais; Ana V. Oliveira; Sofia M. Calado; Gabriela A. Silva. 2015. "Enhancement of chitosan-based transfection efficiency with nuclear localization signal peptides". Trabalho apresentado em European Society of Gene and Cell Therapy, Helsinki, Finlândia, 26 (10).
Ana V. Oliveira; Sofia M. Calado; Gabriela A. Silva. 2015. "Chitosan and hyaluronic acid polyplexes achieve efficient retinal gene delivery". Trabalho apresentado em European Society of Gene and Cell Therapy, Helsinki, Finlândia, 26 (10).
Sofia M. Calado; Liliana S. Alves; Sónia Simão; Bitoque, Diogo; Gabriela A. Silva. 2015. "The role of GLUT1 in the pathogenesis of Diabetic Retinoapthy". Trabalho apresentado em European Society of Gene and Cell Therapy, Helsinki, Finlândia, 58 (1).
Sofia M. Calado; Liliana S. Alves; Sónia Simão; Gabriela A. Silva. 2015. "Hyperglycemia and hypoxia induce overexpression of GLUT1 in models of Diabetic Retinopathy". Trabalho apresentado em European Association for the Study of Diabetes, Estocolmo, Suécia, 58 (1).
Ana V. Oliveira; Sofia M. Calado; Gabriela A. Silva. 2015. Chitosan and hyaluronic acid polyplexes achieve efficient retinal gene delivery. Em European Society of Gene and Cell Therapy.
Joana Morais; Ana V. Oliveira; Sofia M. Calado; Gabriela A. Silva. 2015. Enhancement of chitosan-based transfection efficiency with nuclear localization signal peptides. Em European Society of Gene and Cell Therapy.
Sofia M. Calado; Liliana S. Alves; Sónia Simão; Bitoque, Diogo; Gabriela A. Silva. 2015. The role of GLUT1 in the pathogenesis of diabetic retinopathy. Em European Society of Gene and Cell Therapy.
Sofia M. Calado; Liliana S. Alves; Sónia Simão; Gabriela A. Silva. 2015. Hyperglycemia and hypoxia induce overexpression of GLUT1 in models of diabetic retinopathy. Em European Association for the Study of diabetes.
Machado, S.; Calado, S.; Bitoque, D.; Oliveira, A.V.; Øpstad, C.L.; Zeeshan, M.; Sliwka, H.-R.; et al. 2014. "Cationic Polyene Phospholipids as DNA Carriers for Ocular Gene Therapy". BioMed Research International, 2014. https://doi.org/10.1155/2014/703253
Calado, Sofia M.; Oliveira, Ana V.; Machado, Susana; Haase, Rudolf; Silva, Gabriela A.. 2014. "Sustained Gene Expression in the Retina by Improved Episomal Vectors". Tissue Engineering Part A, 20 (19-20): 2692-2698. https://doi.org/10.1089/ten.tea.2013.0672
Sónia Simão; Bitoque, Diogo; Sofia M. Calado; Gabriela A. Silva. 2014. "Anti-angiogenic VEFG isoform is markedly decreased in the retina of diabetic mice". Trabalho apresentado em European Society of Gene and Cell Therapy, Haia, Países Baixos, 25 (11).
Sofia M. Calado; Berta de la Cerda; Gabriela A. Silva; Bhattacharya, Shom S.; Diaz-Corrales, Francisco J.. 2014. "The role of ATR in retinal cilia formation and elongation". Trabalho apresentado em European Society of Gene and Cell Therapy, Haia, Países Baixos, 25 (11).
Sofia M. Calado; de la Cerda, Berta; Gabriela A. Silva; Bhattacharya, Shom S.; Diaz-Corrales, Francisco J.. 2014. The role of ATR in retinal cilia formation and elongation. Em European Society of Gene and Cell Therapy.
Sónia Simão; Bitoque, Diogo; Sofia M. Calado; Gabriela A. Silva. 2014. Anti-angiogenic VEFG isoform is markedly decreased in the retina of diabetic mice. Em European Society of Gene and Cell Therapy.
Sofia M. Calado; Liliana S. Alves; Gabriela A. Silva. 2013. "Hyperglycemia and oxygen tension control the expression of the glucose transporter GLUT-1 in models of Diabetic Retinopathy". Trabalho apresentado em European Society of Gene and Cell Therapy, Madrid, Espanha, 24 (12).
Sofia M. Calado; Sónia Simão. 2013. pEPito-based vectors enable long-term expression in mouse models of diabetic retinopathy. Em Human Gene Therapy.
Sofia M. Calado; Sónia Simão; Gabriela A. Silva. 2013. "pEPito-based vectors enable long-term expression in mouse models of diabetic retinopathy". Trabalho apresentado em European Society of Gene and Cell Therapy, Madrid, Espanha, 24 (12).
Susana Machado; Sofia M. Calado; Ana V. Oliveira; Susana Jorge; Hans-Richard Sliwka; Vassilia Partali; Michael Pungente; Gabriela A. Silva. 2012. "Novel carotenoid lipid vectors for ocular gene therapy". Trabalho apresentado em European Society of Gene and Cell Therapy, Versailles, França, 23 (10).
Sofia M. Calado; Ana V. Oliveira; Rudolf Haase; Gabriela A. Silva. 2012. "pEPito plasmids: an efficient vector for gene expression in human RPE cells". Trabalho apresentado em European Society of Gene and Cell Therapy, Versailles, França, 23 (10).
Susana Machado; Sofia M. Calado; Ana V. Oliveira; Susana Jorge; Hans-Richard Sliwka; Vassilia Partali; Michael Pungente; Gabriela A. Silva. 2012. Novel carotenoid lipid vectors for ocular gene therapy. Em European Society of Gene and Cell Therapy.
Sofia M. Calado; Ana V. Oliveira; Rudolf Haase; Gabriela A. Silva. 2012. pEPito plasmids: an efficient vector for gene expression in human RPE cells. Em European Society of Gene and Cell Therapy.
Sofia M. Calado; Ana V. Oliveira; Andreia Silva; Susana Machado; Gabriela A. Silva; Rudolf Haase. 2011. Evaluation of new plasmid-based expression systems for gene transfer to the retina. Em XIXth Annual Congress of ESGCT in collaboration with BSGT.
Susana Machado; Sofia M. Calado; Marina I. Santos; Manuel Alvarez-Dolado. 2011. Nanoparticles for controlled release of therapeutic molecules after stroke. Em World Conference on Regenerative Medicine .
Sofia M. Calado; Ana V. Oliveira; Andreia Silva; Susana Machado; Rudolf Haase; Gabriela A. Silva. 2011. "Evaluation of new plasmid-based expression systems for gene transfer to the retina". Trabalho apresentado em European Society of Gene and Cell Therapy, Brighton, Reino Unido, 22 (10).
Sofia M. Calado. 2011. "Evaluation of pEPI-1 and pEPito expression systems for gene transfer to the retina". Mestrado. https://sapientia.ualg.pt/handle/10400.1/10636
