Silhueta de pessoa indiferenciada

Sara Carvalhal

Investigador doutorado
Subsistema
Investigadores
Unidade ID externa
Instituto Gulbenkian de Ciência (IGC)
Regime
Exclusividade
Vínculo
CT em Funções Públicas a termo resolutivo certo
Sara Isabel Guerra Carvalhal Bandarra is a junior group leader at Algarve Biomedical Center - Research Institute, a new institute co-funded by the University of Algarve and Centro Académico de Investigação e Formação Biomédica do Algarve (AD-ABC). In her group, she wants to understand how the chromosome segregation machinery contributes to the aetiology of rare syndromes. She finished her PhD degree in Feb 2016 at the University of Dundee (UK) in Life Sciences. From 2016 to 2020 Sara did her PostDoc funded by an ERC Starting Grant at the Instituto Gulbenkian de Ciência (PT) under Dr.Raquel Oliveira's supervision. In her professional activity interacted with 21 collaborators (s) co-authorship of scientific papers, and worked in four different countries grasping different science environments and multicultural perspectives. Sara Bandarra publishes under the name of Sara Carvalhal and she is the first author of 4 original research articles in Q1 of her field, Cell and Molecular Biology, one as the corresponding author and one published in a special collection of outstanding articles about cell biology of chromosome organisation and segregation. Her later article, Carvalhal et al. 2022 was highly shared across mass media. She has published 5 articles in journals, 4 Conference Abstracts and 12 Posters, being 11 as the first author. She has been selected to give talks in 5 International Scientific meetings (including the highly prestigious international conferences cell-cycle conferences in Roscoff) and invited to give 3 seminars at national institutes. Sara also organised several meetings/events (total of 10, 4 ongoing including 2023 regional FENS at Algarve) and has enrolled in leadership positions by representing her community at the PhD and undergrad studies (PhD representative, PhD committee and Undergrad student committee). She has contributed to the development of science education by supervising 3 undergrad students, 1 Master's student. She was also the main arguer of a Master's thesis as well as by a lab demonstrator at 2 modules of Biological Sciences students at the University of Dundee, 2020 virtual Summer school at Gulbenkian Science Insitute for over 90 students and invited for lectures at the University of Algarve. Sara thinks that science and communication with the community are crucial, therefore she was involved in 12 outreach and science communication activities. Furthermore, she has been involved in peer-reviewing several articles in journals in the field together with her supervisors during her PhD and PostDoc and lately by herself. Sara was awarded the prestigious EMBO Short Term fellowship, a BBSRC PhD Studentship, an FCT PhD Fellowship. In addition, Sara has been awarded for her successful accomplishments during her PhD with the best poster and best image at the University of Dundee out of 200+ participants. As a PI, she was also awarded an FCT CEEC Ind to secure her salary as an independent researcher for the next 6 years. In addition, she got award the prestigious Maratona da Saúde award (single award to Junior category) and choose as L'Oréal Portugal Honor Medals for Women in Science (embargo until 23th March) and an exploratory project (competitive call) awarded by AD-ABC. She is currently involved as a PI in 3 projects; and supervising 3 Master's students and 2 undergrads (one as co-supervisor). CAREER BREAKS: Sara Carvalhal was on maternity leave from Jun 2018 to Oct 2018, followed by a reduced working-hours schedule until Jun 2019.

Atividades

Atividades
2022 - Presente. Arbitragem científica em conferência. 2023 Algarve FENS regional meeting.
2022 - Presente. Arbitragem científica em conferência. Ageing WITHOUT BORDERS - Portuguese Society Stem Cells and Cellular Therapy.
2021/09 - 2022/09. Arbitragem científica em conferência. Institutional Organizer Seminars 2021/2022 Series at ABC-RI.. Algarve Biomedical Center - Research Institute.
2021/09 - 2022/09. Membro de comissão. Founding member of the Career Guidance and Counseling Program 2021/2022 ABC-RI. Coordenador. Algarve Biomedical Center - Research Institute .
2022/01 - 2022/01. Participação em evento. Outreach activity: Lecture to Silves high school students in PT: A estabilidade dos cromossomas.
2021/12 - 2022/01. Curso / Disciplina lecionado. Regente (teacher in charge of a subject) of Oncolab 1 [17161005], Msc in Oncobiology, University of Algarve, PT.. Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado integrado). Universidade do Algarve.
2022/01/22 - 2022/01/22. Entrevista / Programa (rádio / tv). TSF (national radio interview) - Opening line 8am news. . Interview about reserach paper Carvalhal et al 2022 .
2021/11 - 2021/11. Organização de evento. Co-organizer and chair of International Forum Edition 2021. Topic: Neuroscience in health and diseases. (126 registrations). https://abcri.pt/events/abc-ri-fall-international-forumneuroscience-in-health-and-diseases/ (2021).
2021/10 - Presente. Orientação. The molecular mechanisms underlining erroneous segregation on WABS.ONCOBIOLOGIA - MECANISMOS MOLECULARES DO CANCRO (Mestrado). Orientador de Xavier Jorge.
2021/10 - Presente. Curso / Disciplina lecionado. Invited lecture on topic: Cell cycle in Stem Cells (2 hours). Module 17161001 (regente José Bragança) Msc in Oncobiology and Biomedical Science. University of Algarve, PT.. Universidade do Algarve.
2021/10/30 - 2021/10/30. Entrevista / Programa (rádio / tv). Radio interview to the program 'Os dias do Futuro' . Interview about my Maratona da Saúde award.
2021/10/29 - 2021/10/29. Entrevista / Programa (rádio / tv). RTP1 (State financed broadcaste) at the program A tarde é nossa | Maratona da Saúde special program| . To receive Maratona da Saúde award and speak about the objective of this project.
2020/12 - 2021/03. Participação em evento. INVITED to Group Leaders Meeting (By invitation only) - Aneuploidy and CIN Zoom forum - in remembrance of Angelika Amon. Conferência. Aneuploidy and CIN Zoom forum - in remembrance of Angelika Amon - Group Leaders Meeting (By invitation only) .
2021/03/25 - 2021/03/25. Participação em evento. INVITED SPEAKER to share my experiment as a supervisor of Syrian master student. Side event to the Brussels V Conference on Supporting the future of Syria and the region - HIGHER EDUCATION IN CRISIS SETTINGS MATTERS LISTENING TO SYRIAN VOICES AND OTHER TESTIMONIALS. Powered by www.globalplatformforsyrianstudents.org. Conferência. Side event to the Brussels V Conference on “Supporting the future of Syria and the region” - HIGHER EDUCATION IN CRISIS SETTINGS MATTERS – LISTENING TO SYRIAN VOICES AND OTHER TESTIMONIALS..
2021/03/02. Apresentação oral de trabalho. Biallelic mutations in BUB1 cause microcephaly and variable effects on cohesion and chromosome segregation. SELECTED TALK. Cell Cycle Club meeting. Rob de Bruin, Peter Thorpe and John Diffley (London, Reino Unido).
2021/02/23. Apresentação oral de trabalho. Biallelic mutations in BUB1 cause microcephaly and variable effects on cohesion and chromosome segregation. INVITED TALK . Instituto Gulbenkian de Ciência Seminars. Instituto Gulbenkian de Ciência (Oeiras, Portugal).
2020/12. Júri de grau académico. Functional Studies on Zeb Transcription Factors in Glioblastoma
. Arguente principal. Nuno Miguel Mendes Ferreira Ramalho Biomedical Sciences (Mestrado). Universidade do Algarve.
2020/11 - 2020/11. Curso / Disciplina lecionado. Online class for high school students. Seminar of Cell division.. Agrupamento de Escolas de Vila Flor.
2020/11/06. Apresentação oral de trabalho. Biallelic mutations in BUB1 define a novel syndrome with constitutional aneuploidy. INVITED TALK. CBMINARS. University of Algarve - CBMR (FARO, Portugal).
2019/09/13 - 2020/09/13. Orientação. Supervisor of MSc in Biochemistry for Health dissertation work from FCT-UNL. Co-supervisor by Raquel Oliveira, IGC, Portugal. Salma is under the scholarship Global Platform for Syrian Students..MSc in Biochemistry for Health (Mestrado). Orientador.
2020/07 - 2020/07. Curso / Disciplina lecionado. Virtual IGC Undergraduate Summer School 2020. Instituto Gulbenkian de Ciência.
2019/09/27. Apresentação oral de trabalho. The Tale of a Ring: Cohesin in mitosis wonderland. INVITED TALK. CBMINARS. University of Algarve - CBMR (FARO, Portugal).
2019/04/08. Apresentação oral de trabalho. A quantitative analysis of cohesin decay in mitotic fidelity. SELECTED TALK.. Conferérences Jacques-Monod : Mitotic and meiotic cell cycle control and execution. Institut national de la santé et de la recherche médicale - Inserm (Roscoff, França).
2019/02 - 2019/02. Participação em evento. Round table for Research done abroad - Dia dos Mestrados em Ciências 2019, FCUL.. Mesa-redonda. Dia dos Mestrados em Ciências 2019. Universidade de Lisboa Departamento de Química e Bioquímica.
2018/12/17 - 2018/12/17. Participação em evento. Job Shadowing | Scientist for a day. A High school student spends a day with a scientist. Christmas break. Outro. Job Shadowing | Scientist for a day. Instituto Gulbenkian de Ciência.
2018/04/06 - 2018/04/06. Participação em evento. Job Shadowing | Scientist for a day. A High school student spends a day with a scientist. Easter break.. Outro. Job Shadowing | Scientist for a day. Instituto Gulbenkian de Ciência.
2017 - 2017/09/29. Participação em evento. 2017 European Researchers' Night at Pavilhão do Cohencimento, Lisbon. Outro. 2017 European Researchers' Night. Instituto Gulbenkian de Ciência.
2017/07/01 - 2017/09/15. Tutoria. 2017 - Técnico Summer Internships- Quantification of GFP-Rad21WT by live imaging of different fly strains. - . Nina Roothans.
2016/10/01 - 2016/10/01. Participação em evento. Instituto Gulbenkian de Ciência Open Day. Microscopy tours.. Outro. Instituto Gulbenkian de Ciência Open Day..
2015/04/20. Apresentação oral de trabalho. ALADIN, a tale of two divisions – ALADIN is required for proper mitotic and meiotic spindle formation
SELECTED TALK. British Microtubule Meeting.
2014/09/01 - 2015/01/31. Tutoria. Studies of ALADIN in the context of ciliogenisis. . Rachel Yee.
2012/01/15 - 2014/12/31. Membro de comissão. Annual Divisional Retreat for the Centre for Gene Regulation and Expression, University of Dundee, UK. . Membro. University of Dundee.
2014/11/10 - 2014/11/10. Organização de evento. College of Life Science Open Doors Day 2014. I organised the kids' corner activities of this day. (2014). University of Dundee.
2014/11/07 - 2014/11/07. Organização de evento. 2014 Annual Retreat Centre for Gene Expression and Regulation, University of Dundee, UK. Held at Piperdam. (2014). University of Dundee College of Life Sciences.
2014/06/14. Apresentação oral de trabalho. The relation between Triple A syndrome and mitosis. SELECTED TALK. 5th PiCLS Annual Symposium . PhD Students in the College of Life Science, University of Dundee (Dundee, Reino Unido).
2014/04/25. Apresentação oral de trabalho. ALADIN, a tale of two divisions – ALADIN is required for proper mitotic and meiotic spindle formation.SELECTED TALK. British Meiosis Meeting.
2012/10/01 - 2014/03/15. Membro de comissão. Divisional PhD Representative in the Centre for Gene Regulation and Expression, University of Dundee, UK. I represented all the students in my division and took part in the monthly strategic Division's meetings.. Consultor. University of Dundee.
2013/12/01 - 2013/12/15. Curso / Disciplina lecionado. Lab Demonstrator in pratical session Bacterial Genetics. Biological Sciences (Licence). University of Dundee.
2013/11/08 - 2013/11/08. Organização de evento. 2013 Annual Retreat Centre for Gene Expression and Regulation, University of Dundee, UK. Held at Piperdam. (2013). University of Dundee.
2012/11/01 - 2013/11/01. Membro de comissão. PhD Students' Association Committee in the College of Life Sciences (PiCLS) at the University of Dundee. Organisation of Monthly Social Events, PhD student Retreat, Annual Lecture and be the voice of PhD Students for the University Dean.. Membro. University of Dundee.
2013/10/25 - 2013/10/25. Organização de evento. PiCLS Annual Lecture with Prof. Mariano Barbacid from Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain. University of Dundee, UK. (2013).
2013/09/07 - 2013/09/08. Organização de evento. Annual Retreat of PhD Student in College of Life Science , University of Dundee held at Ardroy outdoor activity center, UK. (2013). University of Dundee.
2013/05/17 - 2013/05/17. Arbitragem científica em conferência. 4th PiCLS Symposium 2013. University of Dundee.
2013/01/01 - 2013/01/31. Curso / Disciplina lecionado. Lab Demonstrator in pratical session DNA Module part 1 and 2 . Biomedical Science (Licence). University of Dundee.
2012/11/02 - 2012/11/02. Organização de evento. 2012 Annual Retreat Centre for Gene Expression and Regulation, University of Dundee, UK. Held at Piperdam. (2012). University of Dundee.
2012/06/01 - 2012/08/28. Tutoria. 2012 Summer School - Studies of Ferritin in the context of mitosis. . Aïsha Schofield.
2005/09/01 - 2008/10/15. Membro de comissão. Biochemistry Undergraduate Student Committee. Organise schedules, classes and be the voice of the students at University meetings.. Membro. Universidade de Lisboa Faculdade de Psicologia.

Projetos

Projetos
2012/01/15 - 2015/12/31. Regulation of myosin II filament assembly and stabilisation, localization and cortical anchoring, Wellcome Trust RCDF award. Bolseiro de Doutoramento. Wellcome Trust.
2011/05/11 - 2011/11/15. CENTROSOME-3D Consortium funded project, Consolider-Ingenio. Investigador. Universidad de Cantabria.
2021/12 - 2023/12. Unraveling the contribution of mitotic failure in rare syndromes with microcephaly susceptibility.. Investigador responsável. Universidade do Algarve Algarve Biomedical Center.
2022/06 - 2024/06. Explore the mechanisms behind neurodegenerative rare disorders - is mitosis on the aetiology of these diseases?. Investigador responsável. Algarve Biomedical Center - Research Institute.
2020/09 - 2026/09. QUANTITATIVE COHESIN AND MITOTIC FIDELITY IN THE CONTEXT OF COHESINOPATHIES. Outra. Fundação para a Ciência e a Tecnologia.
2016/01 - 2020/09. Chromosome Architecture and the Fidelity of Mitosis during Development. Bolseiro de Pós-Doutoramento. Instituto Gulbenkian de Ciência.
2015/01/21 - 2015/04/21. Study of ALADIN meiotic function in female mouse oocytes, Short Fellowship. Bolseiro de Doutoramento. University of Dundee.

Produções

Sara Carvalhal; Ingrid Bader; Martin A. Rooimans; Anneke B. Oostra; Jesper A. Balk; René G. Feichtinger; Christine Beichler; et al. 2022. "Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation". Science Advances. https://doi.org/10.1126/sciadv.abk0114
2021. Biallelic BUB1 mutations cause microcephaly, developmental delay and variable effects on cohesion and chromosome segregation. Em SALK virtual-2021-cell-cycle-meeting.
Carvalhal, Sara. 2020. Mutations in the gene BUB1 cause a novel syndrome . Em 24TH Annual Meeting of the Portuguese Society of Human Genetics.
CARVALHAL, SARA; Tavares, Alexandra; Santos, Mariana B.; Mirkovic, Mihailo; Oliveira, Raquel A.. 2018. "A quantitative analysis of cohesin decay in mitotic fidelity". The Journal of Cell Biology, 217 (10): 3343-3353. https://doi.org/10.1083/jcb.201801111
CARVALHAL, SARA; et al. . 2018. A quantitative analysis of cohesin decay in mitotic fidelity. . Em 2018 Portuguese Drosophila Meeting.
CARVALHAL, SARA; Stevense, M.; Koehler, K.; Naumann, R.; Huebner, A.; Jessberger, R.; Griffis, E.R.. 2017. "ALADIN is required for the production of fertile mouse oocytes". Molecular Biology of the Cell, 28 (19): 2470-2478. https://doi.org/10.1091/mbc.E16-03-0158
CARVALHAL, SARA; et al.. 2017. The role of centromeric chromatin forces on mitotic fidelity. . Em 2017 Portuguese Drosophila Meeting.
Ortmann, B.; Bensaddek, D.; CARVALHAL, S; Moser, S.C.; Mudie, S.; Griffis, E.R.; Swedlow, J.R.; Lamond, A.I.; Rocha, S.. 2016. "CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells". Journal of Cell Science, 129 (1): 191-205. https://doi.org/10.1242/jcs.179911
Bandarra, Sara. 2016. "Characterisation of ALADIN’s function during cell division". Doutoramento. https://discovery.dundee.ac.uk/en/studentTheses/characterisation-of-aladins-function-during-cell-division
CARVALHAL, SARA; et al.. 2016. A quantitative understanding of mild sister chromatid cohesion defects in the fidelity of chromosome segregation. . Em 2016 Portuguese Drosophila Meeting.
CARVALHAL, SARA; et al.. 2016. A quantitative understanding of mild sister chromatid cohesion defects in the fidelity of chromosome segregation. . Em 9th EMBO Young Scientists' Forum.
CARVALHAL, S; Ribeiro, S.A.; Arocena, M.; Kasciukovic, T.; Temme, A.; Koehler, K.; Huebner, A.; Griffis, E.R.. 2015. "The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation". Molecular Biology of the Cell, 26 (19): 3424-3438. https://doi.org/10.1091/mbc.E15-02-0113
Carvalhal, Sara. 2015. Celebrating 10 years of Athena SWAN Charter advancing women in science. Guest post at PLOS Blog (currently PLOS ECR Community Blog). https://blogs.plos.org/thestudentblog/2015/06/12/athenaswan/
CARVALHAL, SARA; et al.. 2014. The Nucleoporin ALADIN is Essential for Proper Mitotic Spindle Formation. ALADIN regulates Aurora A localization. Em 2014 American Society for Cell Biology Annual Meeting.
Carvalhal, Sara; Koehler, K ; Huebner, A; Griffis, E. R.. 2014. "The Nucleoporin ALADIN is Essential for Proper Mitotic Spindle Formation.". Trabalho apresentado em ASCB/IFCB Meeting, Philadelphia, PA, Estados Unidos, 25.
Carvalhal, Sara; et al.. 2013. The Nucleoporin ALADIN is Essential for Proper Force Balancing Within Mitotic and Meiotic Spindles.. Em 2013 ASCB Annual Meeting.
CARVALHAL, SARA; et al. . 2013. ALADIN is essential for proper mitotic and meiotic spindle function. . Em EMBO Conference on Meiosis. .
Carvalhal, S.; Geng, Y.; Huebner, A.; Koehler, K.; Jessberger, R.; Griffis, E. R.. 2013. "The Nucleoporin ALADIN is Essential for Proper Force Balancing Within Mitotic and Meiotic Spindles.". Trabalho apresentado em ASCB/IFCB Meeting, New Orleans, LA , Estados Unidos, 24.
Carvalhal, S.I .; Geng, Y.; Huebner, A.; Kohler, K.; Jessberger, R.; Griffis, E. R.. 2013. "The Nucleoporin ALADIN is Essential for Proper Force Balancing Within Mitotic and Meiotic Spindles.". Trabalho apresentado em 2013 ASCB/IFCB Meeting , New Orleans, LA , Estados Unidos, 24.
CARVALHAL, SARA; et al. . 2012. The nucleoporin ALADIN is essential for proper mitotic and meiotic spindle function.. Em 2012 American Society for Cell Biology meeting.
Carvalhal, S.; Arocena, M.; Griffis, E. R.. 2012. "The nucleoporin ALADIN is essential for proper mitotic and meiotic spindle function. ". Trabalho apresentado em ASCB meeting, San Francisco, CA , Estados Unidos, 23. https://doi.org/10.1142/9789814447089_0020
CARVALHAL, SARA; et al. . 2011. Uncovering the role of TBCCD1 in the centrosome-nucleus connection. . Em EMBO Conference on Centrosomes and Spindle Pole Bodies.
Gonçalves, J.; Tavares, A.; CARVALHAL, S; Soares, H.. 2010. "Revisiting the tubulin folding pathway: New roles in centrosomes and cilia". Biomolecular Concepts, 1 (5-6): 423-434. https://doi.org/10.1515/bmc.2010.033
Bandarra, Sara. 2010. "Estudo da proteína humana centrossomal TBCCD1 em condições de stress oxidativo causadas por H202 em estado estacionário". Mestrado. http://hdl.handle.net/10451/5364
Gonçalves, J.; Tavares, A.; CARVALHAL, S; et al.. 2010. TBCCD1 a key protein in the centrosome-nucleus connection is spread through the phylogenetic tree of life. . Em 2010 annual ASCB meeting.
Gonçalves, J.; Tavares, A.; CARVALHAL, S; et al.. 2010. Human TBCCD1 is a key protein in the centrosome-nucleus connection. Why do acentrosomal organisms have it? . Em The Centrosome: Structure, Function and Dynamics Meeting.
 

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